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Mitochondrial DNA and the Immuno-inflammatory Response: New Frontiers to Control Specific Microbial Diseases
Mitochondria are multifunctional organelles that actively participate in the immune-inflammatory response in various pathologies. This volume updates readers on knowledge about mitochondria function. The editors have compiled six chapters about inflammation in its broadest sense, with contributions from active groups of cell biologists, infectologists and pathologists. The chapters in this volume focus on research related to five notable diseases: (1) two diseases (one bacterial and one viral) in which the exacerbation of the inflammatory response can lead to neuropathies: leprosy (one of the oldest diseases in the world) and Zika fever (a disease relatively new in Brazil) (2) three diseases...
Current Diagnosis of Infant Tuberculosis Infection: Title.pdf; 02 Cover and title; 03 REVISED eBooks End User License Agreement-Website; 04 Dedication; 05 Contents; 07 Preface; 08 Contributors; 10 Chapter One II-OK; 11 Chapter Two II-OK; 12 Chapter Three II-OK; 13 Chapter Four II OK; 14 Chapter Five II-OK; 15 Chapter Six II-OK; 16 Chapter Seven II-OK; 17 Chapter Eight II-OK; 18 Appendix; 19 Glossary of Terms; 20 Index
One of the most extraordinary characteristics of Mycobacterium tuberculosis infection is its capacity to remain within the host's tissues for a long period of time. There is an enormous reservoir of persons latently infected with tuberculosis (LTBI) estimated at about a third of the world's population. From this reservoir arise about 10 million new cases of active TB and more than two million deaths occur annually. Current Diagnosis of Infant Tuberculosis Infection covers problems concerning the diagnosis of LTBI, giving an overview of commercially available options and, unlike most reviews on.
Relacionamentos
O livro analisa mitos comuns associados aos relacionamentos amorosos e desvenda suas realidades subjacentes. Começando com a noção de que "os opostos se atraem", a obra enfatiza a relevância da compatibilidade em termos de valores compartilhados. Além disso, o livro desmistifica a crença de que "a paixão deve ser eterna", esclarecendo que a verdadeira intimidade se desenvolve gradualmente com o tempo. Também aborda o mito de que "ciúmes é um sinal de amor", ressaltando que os ciúmes excessivos geralmente refletem insegurança, não amor saudável. A obra destaca a importância de enfrentar desafios nos relacionamentos, desafiando a noção de que "os relacionamentos sempre devem ser simples". Por último, mas não menos importante, o livro sublinha que a compreensão destes mitos é fundamental para construir relacionamentos sólidos, baseados em uma comunicação eficaz, respeito mútuo e desenvolvimento pessoal.
Changing Cultures in Higher Education
More and more educational scenarios and learning landscapes are developed using blogs, wikis, podcasts and e-portfolios. Web 2.0 tools give learners more control, by allowing them to easily create, share or reuse their own learning materials, and these tools also enable social learning networks that bridge the border between formal and informal learning. However, practices of strategic innovation of universities, faculty development, assessment, evaluation and quality assurance have not fully accommodated these changes in technology and teaching. Ehlers and Schneckenberg present strategic approaches for innovation in universities. The contributions explore new models for developing and engag...
Developing Costimulatory Molecules for Immunotherapy of Diseases
Developing Costimulatory Molecules for Immunotherapy of Diseases highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy using either humanized antibodies against CD80, CD86, and other costimulatory molecules or CD28 fusinogenic proteins in the treatment of diseases, including allergies, asthma, rheumatoid arthritis, multiple sclerosis, lupus nephritis, severe psoriasis, vulgaris tuberculosis, thopoid, transplantation therapeutic, cancer, and inflammation. The text aims to provide the latest information on the complex roles and interactions within the CD28 and B7 costimulatory families, with the hope that targeting these families will yield new therapies for the treatment of inflammation, autoimmunity, transplantation, cancer, and other infectious diseases. - Highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy - Provides the latest information on the complex roles and interactions within the CD28 and B7 costimulatory families - Targets new therapies for the treatment of inflammation, autoimmunity, transplantation, cancer, and other infectious diseases
The Epidemiology and Ecology of Leishmaniasis
Leishmaniasis is a vector-borne, parasitic disease with tremendous variety in presentation, biology, and epidemiology. Any book on this disease must acknowledge the nearly impossible task of providing an exhaustive account of leishmaniasis simply because the epidemiology of the disease is so very complex. This book addresses some of this variety with chapters on the epidemiology of leishmaniasis in North Africa, Central America, and South America. The purpose of the book is not to specifically address diagnosis and treatment of the disease, but rather to provide a sample of the differing epidemiologies of leishmaniasis that occur due to variations in local habitats; the presence of different vectors, reservoirs, and agents; and the wide variety of cultures in which this disease occurs.
