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Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.
This book is a printed edition of the Special Issue "Marine Compounds and Cancer" that was published in Marine Drugs
This book highlights analytical chemistry instrumentation and practices applied to the analysis of natural products and their complex mixtures, describing techniques for isolating and characterizing natural products. • Applies analytical techniques to natural products research – an area of critical importance to drug discovery • Offers a one-stop shop for most analytical methods: x-ray diffraction, NMR analysis, mass spectrometry, and chemical genetics • Includes coverage of natural products basics and highlights antibacterial research, particularly important as efforts to combat drug resistance gain prominence • Covers instrumental techniques with enough detail for both current practitioners and beginning researchers
Classical natural product chemistry is transitioning to modern day metabolomics as a result of the advent of comprehensive analytical platforms and sensitive analytical instrumentation. Therefore, it is worthwhile to summarize recent developments with current analytical platforms and highlight how metabolomics is being integrated into this classical field to dereplicate and profile natural product extracts. Metabolomics Tools for Natural Product Discoveries: Methods and Protocols aims to unite diverse and recently developed methodologies and protocols in order to identify bioactive secondary metabolites for the purpose of drug discovery. Some topics covered in this volume include application...
Written by recognized experts in the study of proteins, Proteomics for Biological Discovery begins by discussing the emergence of proteomics from genome sequencing projects and a summary of potential answers to be gained from proteome-level research. The tools of proteomics, from conventional to novel techniques, are then dealt with in terms of underlying concepts, limitations and future directions. An invaluable source of information, this title also provides a thorough overview of the current developments in post-translational modification studies, structural proteomics, biochemical proteomics, microfabrication, applied proteomics, and bioinformatics relevant to proteomics. Presents a comp...
This book provides a comprehensive exploration into the identification and development of sustainable business models as well as their implementation, management and evaluation. With ever-increasing pressure on organisations to respond to societal change and improve competition through sustainable business model innovation (SBMI), this book aims to contribute to the knowledge of their design and management. The chapters explore the role of partnerships, the Internet of Things and the circular economy, among other factors, in developing SBM and how SBMI is facilitated through ideation and in entrepreneurial settings. Providing new typologies, patterns and a framework to evaluate the level of sustainability of business models, this book critically reviews existing literature on the topic to examine the potential of SBMI in research and in practice. The contributing authors employ a number of case studies and case examples to illustrate the integration of sustainable business models throughout the value chain, and their influence on wider social, environmental and business activities.
The emerging field of lipidomics has been made possible because of advances in mass spectrometry, and in particular tandem mass spectrometry of lipid ions generated by electrospray ionization. The ability to carry out basic biochemical studies of lipids using electrospray ionization is predicated upon understanding the behaviour of lipid derived ions following collision induced decomposition and mechanisms of product ion formation. During the past 20 years, a wealth of information has been generated about lipid molecules that are now analysed by mass spectrometry, however there is no central source where one can obtain basic information about how these very diverse biomolecules behave follow...
Fundamentals and Sensing Applications of 2D Materials provides a comprehensive understanding of a wide range of 2D materials. Examples of fundamental topics include: defect and vacancy engineering, doping and advantages of 2D materials for sensing, 2D materials and composites for sensing, and 2D materials in biosystems. A wide range of applications are addressed, such as gas sensors based on 2D materials, electrochemical glucose sensors, biosensors (enzymatic and non-enzymatic), and printed, stretchable, wearable and flexible biosensors. Due to their sub-nanometer thickness, 2D materials have a high packing density, thus making them suitable for the fabrication of thin film based sensor devi...
This volumes consists of 59 peer-reviewed papers, presented at the International Conference on Sustainable Design and Manufacturing (SDM-16) held in Chania, Crete Greece in April 2016. Leading-edge research into sustainable design and manufacturing aims to enable the manufacturing industry to grow by adopting more advanced technologies, and at the same time improve its sustainability by reducing its environmental impact. SDM-16 covers a wide range of topics from sustainable product design and service innovation, sustainable process and technology for the manufacturing of sustainable products, sustainable manufacturing systems and enterprises, decision support for sustainability, and the study of societal impact of sustainability including research for circular economy. Application areas are wide and varied. The book will provide an excellent overview of the latest research and development in the area of Sustainable Design and Manufacturing.
This book consists of peer-reviewed papers, presented at the International Conference on Sustainable Design and Manufacturing (SDM 2021). Leading-edge research into sustainable design and manufacturing aims to enable the manufacturing industry to grow by adopting more advanced technologies and at the same time improve its sustainability by reducing its environmental impact. Relevant themes and topics include sustainable design, innovation and services; sustainable manufacturing processes and technology; sustainable manufacturing systems and enterprises; and decision support for sustainability. Application areas are wide and varied. The book will provide an excellent overview of the latest developments in the sustainable design and manufacturing area.