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The Neurobiology and Genetics of Gilles de la Tourette Syndrome: New Avenues Through Large-Scale Collaborative Projects
Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as hist...
Big Data Analytics in Genomics
This contributed volume explores the emerging intersection between big data analytics and genomics. Recent sequencing technologies have enabled high-throughput sequencing data generation for genomics resulting in several international projects which have led to massive genomic data accumulation at an unprecedented pace. To reveal novel genomic insights from this data within a reasonable time frame, traditional data analysis methods may not be sufficient or scalable, forcing the need for big data analytics to be developed for genomics. The computational methods addressed in the book are intended to tackle crucial biological questions using big data, and are appropriate for either newcomers or...
Causation in Psychology
A renowned philosopher argues that singular causation in the mind is not grounded in general patterns of causation, a claim on behalf of human distinctiveness, which has implications for the future of social robots. A blab droid is a robot with a body shaped like a pizza box, a pair of treads, and a smiley face. Guided by an onboard video camera, it roams hotel lobbies and conference centers, asking questions in the voice of a seven-year-old. “Can you help me?” “What is the worst thing you’ve ever done?” “Who in the world do you love most?” People pour their hearts out in response. This droid prompts the question of what we can hope from social robots. Might they provide humanl...
Handbook of Large-Scale Distributed Computing in Smart Healthcare
This volume offers readers various perspectives and visions for cutting-edge research in ubiquitous healthcare. The topics emphasize large-scale architectures and high performance solutions for smart healthcare, healthcare monitoring using large-scale computing techniques, Internet of Things (IoT) and big data analytics for healthcare, Fog Computing, mobile health, large-scale medical data mining, advanced machine learning methods for mining multidimensional sensor data, smart homes, and resource allocation methods for the BANs. The book contains high quality chapters contributed by leading international researchers working in domains, such as e-Health, pervasive and context-aware computing, cloud, grid, cluster, and big-data computing. We are optimistic that the topics included in this book will provide a multidisciplinary research platform to the researchers, practitioners, and students from biomedical engineering, health informatics, computer science, and computer engineering.
Afflictions
This book is one of the first to integrate psychological and medical anthropology with the methodologies of visual anthropology, specifically ethnographic film. It discusses and complements the work presented in Afflictions: Culture and Mental Illness in Indonesia, the first film series on psychiatric disorders in the developing world, in order to explore pertinent issues in the cross-cultural study of mental illness and advocate for the unique role film can play both in the discipline and in participants’ lives. Through ethnographically rich and self-reflexive discussions of the films, their production, and their impact, the book at once provides theoretical and practical guidance, encouragement, and caveats for students and others who may want to make such films.
Blueprint, with a new afterword
A top behavioral geneticist makes the case that DNA inherited from our parents at the moment of conception can predict our psychological strengths and weaknesses. In Blueprint, behavioral geneticist Robert Plomin describes how the DNA revolution has made DNA personal by giving us the power to predict our psychological strengths and weaknesses from birth. A century of genetic research shows that DNA differences inherited from our parents are the consistent lifelong sources of our psychological individuality—the blueprint that makes us who we are. Plomin reports that genetics explains more about the psychological differences among people than all other factors combined. Nature, not nurture, is what makes us who we are. Plomin explores the implications of these findings, drawing some provocative conclusions—among them that parenting styles don't really affect children's outcomes once genetics is taken into effect. This book offers readers a unique insider's view of the exciting synergies that came from combining genetics and psychology. The paperback edition has a new afterword by the author.
