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The Springer Handbook of Bio-/Neuro-Informatics is the first published book in one volume that explains together the basics and the state-of-the-art of two major science disciplines in their interaction and mutual relationship, namely: information sciences, bioinformatics and neuroinformatics. Bioinformatics is the area of science which is concerned with the information processes in biology and the development and applications of methods, tools and systems for storing and processing of biological information thus facilitating new knowledge discovery. Neuroinformatics is the area of science which is concerned with the information processes in biology and the development and applications of me...
This book constitutes the refereed proceedings of the 9th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2012, held in Houston, TX, USA during in July 2012. The 16 revised full papers presented were carefully reviewed and selected from 23 submissions. The papers are organized in topical sections on relativistic heavy ions and DNA damage; image segmentation; proteomics; RNA and DNA sequence analysis; RNA, DNA, and SNP microarrays; semi-supervised/unsupervised cluster analysis.
"This volume, presented during a symposium in memory of Antonina Starita which was held in Pisa at the Department of Computer Science."--Pref.
Annotation. This book constitutes the thoroughly refereed post-conference proceedings of the Sixth International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2009, held in Genova, Italy, in October 2009. The revised 23 full papers presented were carefully reviewed and selected from 57 submissions. The main goal of the CIBB meetings is to provide a forum open to researchers from different disciplines to present and discuss problems concerning computational techniques in tools for bioinformatics, gene expression analysis and new perspectives in bioinformatics together with 4 special sessions on using game-theoretical tools in bioinformatics, combining Bayesian and machine learning approaches in bioinformatics: state of the art and future perspectives, data clustering and bioinformatics (DCB 2009) and on intelligent systems for medical decisions support (ISMDS 2009).
What happened before the primordial fire of the Big Bang: a theory about the ultimate origin of the universe. In the beginning was the Big Bang: an unimaginably hot fire almost fourteen billion years ago in which the first elements were forged. The physical theory of the hot nascent universe—the Big Bang—was one of the most consequential developments in twentieth-century science. And yet it leaves many questions unanswered: Why is the universe so big? Why is it so old? What is the origin of structure in the cosmos? In An Infinity of Worlds, physicist Will Kinney explains a more recent theory that may hold the answers to these questions and even explain the ultimate origins of the univers...
This book constitutes the thoroughly refereed post-proceedings of the 7th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2010, held in Palermo, Italy, in September 2010. The 19 papers, presented together with 2 keynote speeches and 1 tutorial, were carefully reviewed and selected from 24 submissions. The papers are organized in topical sections on sequence analysis, promoter analysis and identification of transcription factor binding sites; methods for the unsupervised analysis, validation and visualization of structures discovered in bio-molecular data -- prediction of secondary and tertiary protein structures; gene expression data analysis; bio-medical text mining and imaging -- methods for diagnosis and prognosis; mathematical modelling and simulation of biological systems; and intelligent clinical decision support systems (i-CDSS).
Cerebral gliomas account for 45% of all primary central nervous system (CNS) tumors. The median survival after the initial diagnosis of glioblastoma (GBM) is only 15 months, and less than 10% of patients survive three years post-diagnosis. Surgical treatment followed by adjuvant therapies such as radiotherapy and chemotherapy represents the classical strategy in glioma management. The revised WHO 2016 classification now distinguishes the oligodendrogliomas with 1p19q codeletion and IDH mutation from the astrocytomas with or without IDH mutations, thereby creating homogenous and pathologically distinct subgroups. While the status of gene expression and mutations define components of GBM subtypes, it was also found that response to therapies was different for each subtype, suggesting that personalized treatment based on genomic alterations could lead to a more favorable outcome for this disease.
This book constitutes the thoroughly refereed post-conference proceedings of the 10th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2013, held in Nice, France in June 2013. The 19 revised full papers presented were carefully reviewed and selected from 35 submissions. The papers are organized in topical sections on bioinformatics, biostatistics, knowledge based medicine, and data integration and analysis in omic-science.
This book constitutes the thoroughly refereed post-conference proceedings of the 11th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2014, held in Cambridge, UK, in June 2014. The 25 revised full papers presented were carefully reviewed and selected from 44 submissions. The papers focus problems concerning computational techniques in bioinformatics, systems biology, medical informatics and biostatistics.