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Detection of Ischemic Myocardium with Exercise
The detection of ischemic myocardium is one of the major problems in modern cardiology. Exercise has long been used to detect latent myocardial ischemia by enhancing oxygen de mand, but different cardiologists perform exercise tests in dif ferent ways. In addition, many new techniques for detection of ischemia have been developed in the past decade. For these reasons, a symposium on this topic was organized in Dusseldorf under the auspices of the European Society of Cardiology. The papers from this symposium contained herein provide an up-to-date review of the different forms of exercise tests, including their advantages and disadvantages. Indications for study, recording techniques and eval...
Medical and Surgical Management of Tachyarrhythmias
The first cardiovascular operation in Duesseldorf, a ligation of an open ductus arteriosus (Botallo), was performed in 1938 by E.K. Frey. During the Second World War and the subsequent years many difficulties hindered cardiovascular surgery in Duesseldorf. However, it was resumed on 3 May 1949 by Prof. Ernst Derra, again by ligating an open ductus arteriosus. This was the starting pOint of the successful cooperation between the cardiological and surgical working groups - the "birthday" of the Duesseldorf Heart Centre. Further highlights in cardiac surgery were the introduction of open heart surgery by means of surface-cool ing hypothermia (9 February 1955) and extracorporeal circulation (21 ...
Nitrates and Nitrate Tolerance in Angina Pectoris
Although nitroglycerin is one of the oldest drugs in cardiology the problem of tolerance is a scientific challenge of today. The proceedings of this symposium highlight the most re cent questions related to this topic. Apparently, partial tolerance, or rather partial decrease in sensitivity, can arise during nitrate therapy. Probably this is the consequence of a partial readjustment of the vascular system. This readjustment refers particularly to the arterial system, i.e., to the hypoten sive effect of nitrates in the standing position. A similar effect on the venous side is not present. On the other hand, the results assembled in this volume confirm the experience of many decades that long-...
Cardio-Physiology Challenging Empirical Philosophy
With this volume of three essays, the authors want to create an opportunity for dialogue between different disciplines by taking a closer look at three cardio-physiological examples. In the essays presented, we will look at the exploration of different cardiological topics from the 20th century, all of which have contributed to a better understanding of certain aspects of cardiac activity. Not only do these insights provide a more complete picture of these cardiac phenomena, but it is also within this context that we can look for and into the patterns of regularities which govern this living organism. Our goal is to stimulate a dialogue on the philosophy of science in the spirit of Hans Reichenbach.
The World Cup, A Very Peculiar History
In 'The World Cup, A Very Peculiar History', author David Arscott tackles the big subjects at the heart of the beautiful game, including how the tournament first kicked off, the dirty tactics used throughout the years and the most memorable managers in the history of football. Filled to the brim with quirky quotes, fantastic facts and surprising statistics, this is the perfect accompaniment to any post-match celebration (or commiseration!) during the season. At its heart 'The World Cup, A Very Peculiar History' is a look at the many amusing, amazing and sometimes alarming stories that lie behind this great sporting tournament.
A Short History of Cardiology
The story told in this book begins in about 1700, when the first attempts were made to study the diseased heart in life (the subject matter of cardiology), as distinct from its appearance after death; it ends, rather arbitrarily, in 1970. The account of the development of knowledge of heart disease is mainly chronological with emphasis on the fruitful consequences of the cross-fertilization of clinical practice with pathological anatomy at the beginning of the nineteenth century and with physiology at the end. In addition, shorter chapters deals with such topics as specific disease entities, methods of investigation, cardiac surgery and the work of two individuals - Peter Latham, an example of a physician practising with today's clinical skills but a very imperfect knowledge of the pathogenesis of heart disease and Etienne Marey, an early exponent of the clinical physiology which would, in time, throw light on that pathogenesis.
From Molecule to Men
From molecule to man: Medical research has indeed taken this direction, and major improvements of our understanding of the pathophysiology and epidemiology of disease have been achieved. The molecular basis of the congenital cardiovascular disorders has been extended from relatively few congenital malformations into everyday illnesses such as diabetes mellitus, hyperlipoproteinaemea, and arterial hypertension. The monogenic and, more difficult, polygenic basis for a vast majority of cardiovascular disorders are being defined more precisely from year to year. This book gives an overview of what has been achieved so far and defines the current position.
Limitation of Infarct Size
Effective treatment of acute myocardial infarction remains one of the major issues in cardiology and internal medicine. The present monograph summarizes the relevant experimental data and the results of major clinical trials in the treatment of myocardial infarction. There are contributions of fundamental anatomical and physiological concepts of vascular occlusion and myocardial damage due to ischemia as well as discussions of therapeutic strategies involving thrombolytic agents, adjuvant drug therapy for limitation of myocardial damage, improvement in myocardial tolerance to ischemia and prevention of coronary reocclusion. In this regard, there is an extensive discussion of the role of coronary angioplasty and bypass surgery in the setting of acute myocardial infarction.
Advancing the Technology of Bileaflet Mechanical Heart Valves
Over the past 15 years, mechanical valves, and in particular, bileaflet mechanical valves, have made considerable strides in durability and hemodynamic per- formance. However, biocompatibility in terms of thrombo- embolism, thrombosis, and hemolysis has remained an area where improvement is needed. "New Development in Bileaflet Mechanical Heart Valve" discusses advances in these important areas of prosthetic valve function and provides clinical experience with a new open pivot, bileaflet mechanical valve.
Antiarrhythmic Drugs
The past 10 years have seen a remarkable change in the approach to cardiac arrhythmias, from a position of confidence and a feeling of well-being about pharmacological treatment to a situation in which there is now marked uncertainty and general apprehension about the role of antiarrhythmic drugs. Until relatively recently the prevailing concept in antiarrhythmic therapy was that arrhythmias could be controlled by drugs which slowed conduction or suppressed automaticity, goals well served by the sodium channel-blocking drugs and glycosides. Drug re search was based largely on the development of agents mimicking those already available, but with greater efficacy, fewer side effects or a more ...
