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R-Factors: Their Properties and Possible Control
Organized by Sandoz Research Institute
Comprehensive Natural Products II
This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas am...
Advances in Lipid Research
Advances in Lipid Research, Volume 23 provides information pertinent to mammalian as well as plant metabolism. This book presents important data on apoproteins, which may offer a foothold for further probes of the genetics underlying increased susceptibility to ischemic heart disease. Organized into seven chapters, this volume begins with an overview of the molecular biology of human apolipoproteins B and E. This text then explains the lipid metabolism of dermatophytes and describes their lipid composition and how it may be modulated. Other chapters consider the function, distribution, and biosynthesis of the sterols of fungi and examine the influences of fungal sterols on membrane fluidity. This book discusses as well the biosynthesis and degradation of platelet-activating factor (PAF) as well as its physiological function. The final chapter deals with one specific area of PAF activity, namely, renal processes. This book is a valuable resource for biologist, biochemists, chemists, and clinicians.
Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques
Contents: V. Zingel, C. Leschke and W. Schunack: Developments in research on histamine (H1) receptor agonists / P.D. Hoeprich: Antifungal chemotherapy / G. de Stevens: The diversity of heterocyclic compounds and their biological activities / R.M. Schultz: Newer antifolate compounds in cancer therapy / P.K. Mehrotra, S. Batra and A.P. Bhadun: Non-steroidal agents for regulation of the menstrual cycle / A.K. Saxena and M. Saxena: Developments in anti-convulsant drugs
Advances in Microbial Physiology
Advances in Microbial Physiology
Lipids of Pathogenic Fungi (1996)
Increases in various fungal infections due to Candida, Aspergillus, Blastomyces, Histoplasma spp., and Dermatophytes have attracted interest in the biochemistry of the fungal pathogens responsible. This book discusses the importance of lipids in pathogenic fungi and how they are involved in infections that pose serious health problems. The role of lipids in dimorphism, adherence, and virulence of fungi is investigated as is their composition and metabolism. Several chapters are devoted to examinations of specific pathogenic fungi, which will be particularly useful to researchers studying the clinical manifestations of infections caused by these factors. Later chapters present possible antifungal agents and nonconventional agents that target the organisms discussed earlier. Collectively, the contributions to this volume provide an excellent overview of this field. This text is essential for practicing clinicians and for everyone involved in the important task of resolving the problems associated with fungal pathogenicity.
Regional Parliaments
In an attempt to strengthen the legitimacy of European Union (EU) policy-making, the 2009 Lisbon Treaty strengthened the principle of parliamentary control in EU affairs. This pertains to parliaments at all levels ranging from the regional to the supranational level. This book analyses the potential of regional parliaments – the parliaments closest to the citizens – to engage in EU affairs and to fill the perceived legitimacy gap. Eight member states have a total of 73 regional parliaments with legislative powers, and there are further trends towards decentralization in Europe. On its quest to understand the role that regional parliaments can plan in the EU multi-level parliamentary system, the book addresses key questions: What are the formal powers and functions of regional parliaments in EU policy-making? How do they use their powers in practice? How active are they in EU politics, and what do they try to achieve? What factors can explain their degree of (in-)activity? The chapters in this book were originally published in a special issue of The Journal of Legislative Studies.
Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population l...
