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Pharmaceutical Inhalation Aerosol Technology, Second Edition
This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosol. It analyzes the latest science and developments in the generation, administration and characterization of these compounds, showcasing current clinical applications, the efficiency and limitations of major aerosol products and emerging aerosol therapies impacting the field.
Particle-Lung Interactions
Written by an expanded team of leading international scientists, the second edition thoroughly investigates research and therapies for managing adverse physiological effects of air-borne particles on the respiratory tract. The book examines the lung as the gateway for particle damage to organs outside the respiratory system and provide the informat
Nanostructured Biomaterials for Overcoming Biological Barriers
This book provides a critical overview of the advances being made toward overcoming biological barriers through the contribution of nanosciences and nanotechnologies to solve the problems of many current drugs and vaccines.
Drug Absorption Studies
This is a well thought-out, highly practical text covering contemporary ‘in vitro’ techniques for drug absorption studies. Starting at the molecular level of investigation, it continues with cell monolayer models (both primary and cell lines) and culminates with in situ techniques as a final testing format. In addition, chapters on high-throughput assays, in vitro-in vivo correlation, bioinformatics and regulatory issues are covered, giving a comprehensive overview of available models and techniques. Moreover, an appendix consisting of a number of practical protocols is available online, updated as needed, and should prove very helpful to apply the techniques directly to the benchside.
Controlled Pulmonary Drug Delivery
The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and release through sophisticated particle technologies. The large number of contributions to the scientific literature and variety of excellent texts published in recent years is evidence for the continued interest in pulmonary drug delivery research. This reference text endeavors to bring together the fundamental theory and practice of controlled drug delivery to the airways that is unavailable elsewhere. Collating and synthesizing the material in this rapidly evolving field presented a challenge and ultimately a sense of achievement that is hopefully reflected in the content of the volume.
Adhesion
Emphasizing the most recent developments this book addresses both the basic and applied aspects of adhesion. The authors present the latest results on fundamental aspects, adhesion in biology, chemistry for adhesive formulation, surface chemistry and the pretreatment of adherends, mechanical issues, non-destructive testing and the durability of adhesive joints, as well as advanced technical applications of adhesive joints. Prominent scientists review the current level of knowledge concerning the role of chemical bonds in adhesion, new resins and nanocomposites for adhesives, and about the role played by macromolecular architecture in the properties of hot melt and pressure sensitive adhesives. Written by 34 acknowledged experts from academic and industrial research facilities, this is a valuable source of information for chemists, physicists, biologists and engineers, as well as graduate students interested in fundamental and practical adhesion.
American Pharmacy (1852-2002)
Essays reprinted from the Journal of the American Pharmaceutical Association series commemorating the sesquicentennial of the American Pharmaceutical Association.
The History of Pharmacy
Originally published in 1995, The History of Pharmacy is a critical bibliography of selected information on the history of pharmacy. The book is designed to guide students and academics through the history of science and technology. Topics range from medicine, chemical technology and the economics and business of pharmacy to pharmacy’s influence in the arts. The bibliography includes an exhaustive selection of primary and secondary sources and is arranged chronologically. This book will be of interest to those researching in the area of the history of science and technology and will appeal to students and academic researchers alike.
Advances in Pulmonary Drug Delivery
The respiratory tract has been used to deliver biologically active chemicals into the human body for centuries. However, the lungs are complex in their anatomy and physiology, which poses challenges to drug delivery. Inhaled formulations are generally more sophisticated than those for oral and parenteral administration. Pulmonary drug development is therefore a highly specialized area because of its many unique issues and challenges. Rapid progress is being made and offers novel solutions to existing treatment problems. Advances in Pulmonary Drug Delivery highlights the latest developments in this field.
