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Developmental Neuroendocrinology
In this book, experts in the field discuss the latest research in developmental neuroendocrinology. Given that the hypothalamus is the center of neuroendocrine activity, the reader will learn about the molecular specification of hypothalamic cells, developmental modulators and epigenetic factors influencing hypothalamic development, and the development of neuroendocrine circuits. Each chapter provides a concise review of the current and future perspectives in developmental neuroendocrinology. Important insights into state-of-the-art techniques applied to functional circuit tracking, lineage tracing of hypothalamic cells, and the identification of genes altered through epigenetic mechanisms a...
The Brain in Your Kitchen
Every day, we're faced with choices about what to eat, wear, and purchase. Blinded by a tsunami of information—some good, some bad, some intentionally misleading—often our brains are too overwhelmed to examine all the details. So how do we know we're making the best decisions for us? Author and science journalist David DiSalvo asks what's best for our brains instead. The Brain in Your Kitchen sifts through the good and bad information on the things we buy, the foods we eat, and the medicines we take. Using findings from cutting-edge science, DiSalvo divulges terrifically useful and little-known facts—each grounded in credible research—about everything from how gluten to cats affect your brain. Learn how we can trick our minds into helping us lose weight, what placebos are costing us big bucks with no results, and what caffeine is actually doing inside your head to give you that extra pep. Disalvo cuts through frantic media sensation and consumer marketplace babble and gives you the knowledge to distinguish hyperbole from truth so you're ready next time you sit down for dinner.
Building the gateway to consciousness – about the development of the thalamus
Since years, patterning and function of some brain parts such as the cortex in the forebrain and the optical tectum or cerebellum in the midbrain/hindbrain region are under strong investigation. Interestingly the diencephalon located in the caudal forebrain has been ignored for decades. Consequently, the existing knowledge from the development of this region to function in the mature brain is very fragmented. The central part of the diencephalon is the thalamus. This central relay station plays a crucial role in distributing incoming sensory information to appropriate regions of the cortex. The thalamus develops in the posterior part of the embryonic forebrain, where early cell fate decisions are controlled by local signaling centers. In this Research Topic we discuss recent achievements elucidating thalamic neurogenesis - from neural progenitor cells to highly specialized neurons with cortical target cells in great distance. In parallel, we highlight developmental aspects leading from the early thalamic anlage to the late the organization of the complex relay station of the brain.
Science and Psychiatry
Solomon Snyder has been instrumental in the establishment of modern psychopharmacology -- as a pioneer in the identification of receptors for neurotransmitters and drugs and in the explanation of the actions of psychotropic agents. Science and Psychiatry is a collection of some of his best scientific papers, publications ranging over forty years that represent important advances in psychopharmacology and molecular biology. Audacious and unanticipated when they first appeared, these papers opened up new areas of understanding and revolutionized the modern study of the brain. Republished here, they show why fundamental research into the "messengers of the mind" is as essential for clinicians a...
Emerging Roles of Long Noncoding RNAs in Neurological Diseases and Metabolic Disorders
Long noncoding RNAs (lncRNAs) are a new class of transcripts that are in general longer than 200 nucleotides and that have no protein-coding potential. The vast majority of vertebrate genomes encode diverse and complex lncRNAs that play regulatory roles at almost every step of gene expression. Recently, increasing evidence has implicated lncRNAs in the pathogenesis of various human diseases. The purpose of the Research Topic, "Emerging roles of long noncoding RNAs in neurological diseases and metabolic disorders", is to bring together leading researchers in the field who, through contributing to an organized and comprehensive collection of peer-reviewed articles, provide a broad perspective on the latest advances in the field. A number of interesting and cutting-edge areas will be covered as below, but this list is not exclusive: - The methodologies and technologies of identifying and studying lncRNAs - LncRNAs in gene-specific transcription - LncRNAs in epigenetic regulation - LncRNAs in post-transcriptional regulation - LncRNAs in disease - Mapping of noncoding single nucleotide polymorphisms associated with disease.
Neurobiology of Aggression
Aggression is a highly conserved behavioral adaptation that evolved to help org- isms compete for limited resources and thereby ensure their survival. However, in modern societies where resources such as food, shelter, etc. are not limiting, aggr- sion has become a major cultural problem worldwide presumably because of its deep seeded roots in the neuronal circuits and neurochemical pathways of the human brain. In Neurobiology of Aggression: Understanding and Preventing Violence, leading experts in the fields of the neurobiology, neurochemistry, genetics, and behavioral and cultural aspects of aggression and violence provide a comprehensive collection of review articles on one of the most im...
Illuminating Disease
An illustrated introduction to green fluorescent proteins, one of the most important medical research techniques currently available.
Stem Cells in Neuroendocrinology
This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in achieving the derivation of a specific type of neuron. The dopamine neuron offers an important example and is discussed in more detail. Additional chapters cover problems obviously approachable with cells derived from stem cells, including their need in surgeries for pituitary cancers. The last chapter provides an overview of this particular field of research and presents a vision for its future directions.
Long Non Coding RNA Biology
This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. Written by leading experts in the field, it motivates young researchers around the globe, and offers graduate and postgraduate students fascinating insights into genes and their regulation in eukaryotes and higher organisms.
