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Membrane Transporter Diseases
  • Language: en
  • Pages: 382

Membrane Transporter Diseases

Every cell and organism faces the problem of spaces, made up of the two leaflets of the lipid generating a confined space in which metabolic bilayer. The importance of traffic and signaling across membranes is reflected by the estimate and anabolic reactions take place and at the same time allowing entry and exit of metabo that 20% of all genes in the human genome encode membrane proteins. A failure of any of lites, ions, proteins, and signals across its bor der. Evolution has solved the problem by these proteins may have dramatic con se generating lipid membranes that contain trans quences for ceH function. In recent years much porters, ion channels, and receptors. In eukary attention has b...

Responding to Intimate Partner Violence and Sexual Violence Against Women
  • Language: en
  • Pages: 66

Responding to Intimate Partner Violence and Sexual Violence Against Women

A health-care provider is likely to be the first professional contact for survivors of intimate partner violence or sexual assault. Evidence suggests that women who have been subjected to violence seek health care more often than non-abused women, even if they do not disclose the associated violence. They also identify health-care providers as the professionals they would most trust with disclosure of abuse. These guidelines are an unprecedented effort to equip healthcare providers with evidence-based guidance as to how to respond to intimate partner violence and sexual violence against women. They also provide advice for policy makers, encouraging better coordination and funding of services...

Hemochromatosis
  • Language: en
  • Pages: 622

Hemochromatosis

Once thought rare, hemochromatosis is now acknowledged as one of the commonest inherited disorders, affecting one in two hundred people of western Caucasian descent. It is estimated to affect over one million people in the USA alone. This is the most comprehensive clinical reference yet on hemochromatosis. The international author team includes specialists in internal medicine, hematology, hepatology, genetics, biochemistry and molecular biology, and the contents cover all aspects of pathophysiology, epidemiology, diagnosis and treatment. The latest developments in the genetics of the disorder are well explained, and there are sections on screening, diagnostic techniques, and clinical complications. Social and ethical issues are also considered. Highly illustrated, up-to-date and authoritative, this is the definitive resource for all clinicians involved in the management of hemochromatosis, and will also be invaluable to scientists interested in iron metabolism and iron overload.

Inherited Susceptibility to Cancer
  • Language: en
  • Pages: 480

Inherited Susceptibility to Cancer

Many cancers, both common and rare, are known to have a hereditary predisposition and advances in genetics have clarified the risks and in some cases the mechanisms of cancer developing in an individual. First published in 1998, this important contribution to the literature of cancer genetics covers all the key issues, reviewing both the technology behind genetic risk assessment and the ethical dilemmas it poses. It is divided into two parts. The first deals with ethical, legal and social issues. The second systematically outlines current knowledge of the inheritance patterns of many different cancer types, both from a site-by-site perspective and for special groups. This authoritative volume will be of interest to oncologists, physicians and surgeons in other specialities and to health professionals in the areas of primary care, counselling and cancer risk assessment.

Domestic Violence and Mental Health
  • Language: en
  • Pages: 122

Domestic Violence and Mental Health

People with mental health problems are more likely to be a victim of domestic violence than the general population. This text offers practical guidance on how mental health professionals can identify and respond to domestic violence experienced by their patients.

Making Use of Guidelines in Clinical Practice
  • Language: en
  • Pages: 230

Making Use of Guidelines in Clinical Practice

Shares knowledge and best practice on the development, dissemination and implementation of clinical practice guidelines, drawing on current examples from primary and secondary care including both local and national projects.

Genomics and Health in the Developing World
  • Language: en
  • Pages: 1569

Genomics and Health in the Developing World

Genomics and Health in the Developing World provides detailed and comprehensive coverage of population structures, human genomics, and genome variation--with particular emphasis on medical and health issues--in the emerging economies and countries of the developing world. With sections dedicated to fundamtals of genetics and genomics, epidemiology of human disease, biomarkers, comparative genomics, developments in translational genomic medicine, current and future health strategies related to genetic disease, and pertinent legislative and social factors, this volume highlights the importance of utilizing genetics/genomics knowledge to promote and achieve optimal health in the developing worl...

Genetics of Infectious Disease Susceptibility
  • Language: en
  • Pages: 252

Genetics of Infectious Disease Susceptibility

"Progress in the molecular analysis of genetic susceptibility to human and animal infectious diseases has been very rapid over the last few years. Several genes involved in resistance to HIV/AIDS, tuberculosis, malaria, viral hepatitis, herpesvirus infections, prion diseases, and several others have now been identified, and their functions have partly or completely been elucidated." "This book covers the most recent advances in the field and explores how progress in knowing the genetic basis of infectious diseases could lead to new insights into understanding and combating them."--BOOK JACKET.

The Evidence-Based Primary Care Handbook
  • Language: en
  • Pages: 329

The Evidence-Based Primary Care Handbook

  • Type: Book
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  • Published: 2023-07-28
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  • Publisher: CRC Press

Here at last is a realistic and practical book that shows how evidence-based practice can be successfully applied in a primary care setting. The first section provides an introduction to the principles of evidence-based health care as they apply to primary care, and many other books on this subject stop right there. However, Section 3 practises what this first section preaches, by applying these tools to 15 common clinical problems in primary care, such as sore throat, asthma, urinary tract infections, low back pain and heart failure. In between, Section 2 focuses on topics of particular relevance to planners and to Primary Care Groups (PCGs), and includes chapters on commissioning, prescrib...

Oxford Handbook of Public Health Practice
  • Language: en
  • Pages: 467

Oxford Handbook of Public Health Practice

  • Type: Book
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  • Published: 2013-02-28
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  • Publisher: OUP Oxford

Fully revised and updated for the third edition, the Oxford Handbook of Public Health Practice remains the first resort for all those working in this broad field. Structured to assist with practical tasks, translating evidence into policy, and providing concise summaries and real-world issues from across the globe, this literally provides a world of experience at your fingertips. Easy-to-use, concise and practical, it is structured into seven parts that focus on the vital areas of assessment, data and information, direct action, policy, health-care systems, personal effectiveness and organisational development. Reflecting recent advances, the most promising developments in practical public health are presented, as well as maintaining essential summaries of core disciplines. This handbook is designed to assist students and practitioners around the world, for improved management of disasters, epidemics, health behaviour, acute and chronic disease prevention, community and government action, environmental health, vulnerable populations, and more.