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New Methods and Sensors for Membrane and Cell Volume Research
New Methods and Sensors for Membrane and Cell Volume Research, Volume 88 provides an overview of novel experimental approaches to study both the cell membrane and the under-membrane space – the cytosol, which have lately began drawing renewed attention. The book's overall emphasis is on fluorescent and FRET-based sensors, however, other optical (such as variants of transmission microscopy) and non-optical methods (neutron scattering and mass spectrometry) also have dedicated chapters. This volume provides a rare review of experimental approaches to study intracellular phase transitions, as well as anion channels, membrane tension and dynamics, and other topics of intense current interest. - Describes novel FRET-based membrane sensors - Reviews selected non-optical approaches to membrane structure and dynamics - Describes traditional and modern aspects of cell volume research, such as phase transitions and macromolecular crowding
Imaging from Cells to Animals In Vivo
Imaging from Cells to Animals In Vivo offers an overview of optical imaging techniques developed over the past two decades to investigate biological processes in live cells and tissues. It comprehensively covers the main imaging approaches used as well as the application of those techniques to biological investigations in preclinical models. Among the areas covered are cell metabolism, receptor-ligand interactions, membrane trafficking, cell signaling, cell migration, cell adhesion, cytoskeleton and other processes using various molecular optical imaging techniques in living organisms, such as mice and zebrafish. Features Brings together biology and advanced optical imaging techniques to pro...
Environmental Applications of Geochemical Modeling
An application of geochemical modeling to environmental problems, illustrated with case studies of real-world environmental investigations.
Claretta
A master historian illuminates the tumultuous relationship of Il Duce and his young lover Claretta, whose extraordinarily intimate diaries only recently have become available Few deaths are as gruesome and infamous as those of Benito Mussolini, Italy’s fascist dictator, and Claretta (or Clara) Petacci, his much-younger lover. Shot dead by Italian partisans after attempting to flee the country in 1945, the couple’s bodies were then hanged upside down in Milan’s main square in ignominious public display. This provocative book is the first to mine Clara’s extensive diaries, family correspondence, and other sources to discover how the last in Mussolini’s long line of lovers became his intimate and how she came to her violent fate at his side. R. J. B. Bosworth explores the social climbing of Claretta’s family, her naïve and self-interested commitment to fascism, her diary’s graphically detailed accounts of sexual life with Mussolini, and much more. Brimful of new and arresting information, the book sheds intimate light not only on an ordinary-extraordinary woman living at the heart of Italy’s totalitarian fascist state but also on Mussolini himself.
Cellular Diagnostics
This book is the updated English version of the 2006 German bestseller Zellulare Diagnostik, a comprehensive presentation of flow cytometry and its applications. While some techniques of immunophenotyping by flow cytometry already are routine procedures in the laboratory, new methods for the functional characterization of cells, the analysis of rare cells, and the diagnosis of complex materials have only begun to win wide recognition. New approaches such as slide-based cytometry will lead to an increase in the use of cytometric techniques. Multiparameter approaches will further improve analysis. The book provides a comprehensive and detailed compilation of all aspects of flow cytometry in research and the clinic. For newcomers it offers a thorough introduction, for advanced users, specific protocols and interpretation assistance.
Numerical Computations with GPUs
This book brings together research on numerical methods adapted for Graphics Processing Units (GPUs). It explains recent efforts to adapt classic numerical methods, including solution of linear equations and FFT, for massively parallel GPU architectures. This volume consolidates recent research and adaptations, covering widely used methods that are at the core of many scientific and engineering computations. Each chapter is written by authors working on a specific group of methods; these leading experts provide mathematical background, parallel algorithms and implementation details leading to reusable, adaptable and scalable code fragments. This book also serves as a GPU implementation manual for many numerical algorithms, sharing tips on GPUs that can increase application efficiency. The valuable insights into parallelization strategies for GPUs are supplemented by ready-to-use code fragments. Numerical Computations with GPUs targets professionals and researchers working in high performance computing and GPU programming. Advanced-level students focused on computer science and mathematics will also find this book useful as secondary text book or reference.
