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Magical Manhattan
Elijah, a towering Rasta, asks a sad young trekker named Sam to give up his sneakers. Grasses and vines spill over the tops of the skyscrapers, and Fifth Avenue becomes a rushing river. Sam and friends are on a quest to save their beloved city. The princess of magical Manhattan is depending on them.
Forty Impressions
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High Throughput Screening Methods
High throughput screening remains a key part of early stage drug and tool compound discovery, and methods and technologies have seen many fundamental improvements and innovations over the past 20 years. This comprehensive book provides a historical survey of the field up to the current state-of-the-art. In addition to the specific methods, this book also considers cultural and organizational questions that represent opportunities for future success. Following thought-provoking foreword and introduction from Professor Stuart Schreiber and the editors, chapters from leading experts across academia and industry cover initial considerations for screening, methods appropriate for different goals ...
Analysis of Growth Factor Signaling in Embryos
Developmental biologists have been driven to investigate growth factor signaling in embryos in order to understand the regulatory mechanisms underlying a given developmental process. Thus, it is critical to explore the technical methods and experimental designs for growth factor signaling in embryos. Focusing on specific pathways or pathway comp
Rho GTPases
Members of the Rho family of small GTP-binding proteins (GTPases) are key signal transduction proteins that mediate signals initiated by growth factors, cytokines and cell adhesion proteins. Our knowledge about Rho GTPases has rapidly expanded over the past several years and Rho GTPases is the first book to provide a comprehensive overview of the regulation and functions of this important class of proteins. This book includes several chapters dedicated to the review of various classes of proteins that control the localization and activation state of Rho GTPases. Additional chapters discuss the wide range of biological functions that are controlled by Rho GTPases, including the organization of the actin cytoskeleton, cell proliferation and cell motility. Rho GTPases is essential reading for cell and molecular biologists, biochemists and geneticists. The critical roles of Rho family members in cancer and inflammatory diseases makes Rho GTPases also an invaluable guide for clinical investigators and pharmacologists.
Minding the Weather
A detailed study of research on the psychology of expertise in weather forecasting, drawing on findings in cognitive science, meteorology, and computer science. This book argues that the human cognition system is the least understood, yet probably most important, component of forecasting accuracy. Minding the Weather investigates how people acquire massive and highly organized knowledge and develop the reasoning skills and strategies that enable them to achieve the highest levels of performance. The authors consider such topics as the forecasting workplace; atmospheric scientists' descriptions of their reasoning strategies; the nature of expertise; forecaster knowledge, perceptual skills, and reasoning; and expert systems designed to imitate forecaster reasoning. Drawing on research in cognitive science, meteorology, and computer science, the authors argue that forecasting involves an interdependence of humans and technologies. Human expertise will always be necessary.
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