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Free Radical Biology and Environmental Toxicity
The main aim of this book is to collect a series of research articles and reviews from a diverse group of scientists to share their research work on the role of free radical research and environmental toxicity. This book presents various state-of-the-art chapters of recent progress in the field of cellular toxicology and clinical manifestations of various disorders. Topics include cell signaling, various risk factors, the pathophysiology of disease instigation and distribution, mechanistic insights into metal and nanoparticle toxicity, neural toxicity, nongenotoxic carcinogenicity, immune and idiosyncratic toxicity, prevention, biomarkers related to disease progression and therapeutic strategies. In particular, this book provides valuable insight for researchers, pathologists, and clinicians with an interest in toxicological research and cellular impairments with special emphasis on therapeutic advancement.
Transanal Endoscopic Microsurgery
Cancer of the rectum continues to be a significant health problem in industrialized co- tries around the world. Relative 5-year survival rates in the USA for cancer of the rectum from 1995 to 2001 improved to 65%, a 15% improvement over 20 years (American Cancer Society, 2007). The reasons for this dramatic improvement include more accurate pr- perative staging, aggressive neoadjuvant therapy and improved surgical technique as well as specialty-trained surgeons. Despite advances in nonoperative techniques of radiation therapy, chemotherapy and immunotherapy, surgical extirpation continues to be the cornerstone of curative treatment of this potentially lethal disease. Radical cancer excision ...
Encyclopedia of Addictions
This two volume set contains frank and factual information about symptoms, causes, effects, prevention, and treatment of substance abuse—alcohol, nicotine, and drugs—and of behavioral addictions such as eating disorders, pathological gambling, and compulsive sexual activity. Including the most up-to-date research, the addiction entries are based largely on criteria established by the American Psychiatric Association in its Diagnostic and Statistical Manual of Mental Disorders.Tracing the history of the debate over whether addiction is a choice or a disease, the volumes explain how genetic and biological findings support the disease concept while lifestyle choices affect the course of the disease. Graphics and discussions of the brain structures that support this self-reinforcing mechanism illustrate why treatments that obstruct the pathway are showing such promise.
Ventilator-Induced Lung Injury
This reference surveys current best practices in the prevention and management of ventilator-induced lung injury (VILI) and spans the many pathways and mechanisms of VILI including cell injury and repair, the modulation of alveolar-capillary barrier properties, and lung and systemic inflammatory consequences of injurous mechanical ventilation. Cons
Cystogenesis
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secreti...
Pain 2012 Refresher Courses: 14th World Congress on Pain
Pain 2012: Refresher Courses, 14th World Congress on Pain, is based on IASP's refresher courses on pain research and treatment. Includes techniques (neuroimaging, genetics), treatments (interventional, psychological, pharmacological, complementary/alternative), and disorders (neuropathic pain, headache, cancer pain, musculoskeletal pain, CRPS, orofacial pain, postoperative pain, pediatric pain, abdominopelvic pain).
Cereal Grains for the Food and Beverage Industries
Cereals are a staple of the human diet and have a significant effect on health. As a result, they are of major significance to the food industry. Cereal grains for the food and beverage industries provides a comprehensive overview of all of the important cereal and pseudo-cereal species, from their composition to their use in food products.The book reviews the major cereal species, starting with wheat and triticale before covering rye, barley and oats. It goes on to discuss other major species such as rice, maize, sorghum and millet, as well as pseudo-cereals such as buckwheat, quinoa and amaranth. Each chapter reviews grain structure, chemical composition (including carbohydrate and protein...
Emergency Surgery in Obese Patients
This comprehensive, multi-authored book covers all aspects of surgery on obese patients in emergency conditions. Obesity is a metabolic disease affecting a high percentage of world population.. It involves marked anthropometric changes, affecting surgical practice and altering patients’ ability to react to surgical stress. The prevalent comorbidities also affect the rate of complications and mortality after surgery. The obesity paradox, the ability of obese patients to survive emergency operations in spite of an increased risk of complications, is an effect of the widespread development of “Obesity Science”. This volume discusses this science, examining the frailty of the obese patients and the main comorbidities that affect clinical practice, as well as the most frequent emergency situations after trauma, inflammatory diseases and the complications of bariatric surgery. With contributions from leading experts, it provides clinicians with detailed and updated information for better practice in this emerging field of surgery.
Rye and Health
Rye has been known to stimulate weight loss, prevent gallstones, lower the risk of type 2 diabetes, promote gastrointestinal health, and improve cardiovascular conditions. Due to rye s many health benefits, it s no wonder that nutritionists, the grains industry, and in turn consumers, have been giving this healthy grain much more attention. Rye and Health, edited by veteran food technology and nutrition scientists Kaisa Poutanen and Per Åman, explains in detail the composition of rye and its physiological and health effects on humans using the latest research and information available.--
