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Principles and Practice of Research
emerging on the surgical scene to challenge or For some readers, the title of this book will im thodoxy. Although these innovations are often mediately raise the question, what exactly is greeted with great optimism, a factual basis for meant by surgical research? In the very broadest that enthusiasm is sometimes far from secure sense the term can be taken to include all en and much further work is frequently required to deavors, however elementary or limited in discover whether we are dealing with genuine scope, to advance surgical knowledge. Ideally, advances or not. it refers to well-organized attempts to establish The most exciting and attractive scenario for on a proper scientific basis, i. e. , to place beyond surgical research is unquestionably one that de reasonable doubt, the truth or otherwise of any picts a successful attempt by a researcher to es concepts, old or new, within the ambit of sur gery, and, of course, anaesthesia. tablish the accuracy of some bold innovation for which he himself is responsible. Joseph Lister, The methods used to achieve that end vary demonstrating by clinical trial that wound sup enormously, depending on the issue being in vestigated.
Surgical Research
A unique reference manual for academic surgeons, this book discusses every facet of surgical research. From getting grant money to choosing a topic, reviewing the literature, planning and conducting research, and reporting results.
Surgery of the Stomach
This is a carefully illustrated volume of surgical procedures. Well-known standard as well as alternative procedures in surgery of the stomach and the proximal duodenum are depicted with anatomical exactness. Possible complications, errors, and dangers and how to avoid them are discussed in detail. Each operative step is illustrated superbly and accompanied by a short, precise text. Both illustrations and text stem from the practical experience in the operating theater of the many renowned surgeons who have contributed to this volume. The book serves as an indispensable reference for surgeons; likewise, gastroenterologists, radiologists, pathologists, and anatomists will find this volume of immeasurable value in their daily work.
Gastric Cancer
Gastric cancer is still the most common cause of cancer death in the world, although in most countries, with the notable exception of the United States, its incidence is slowly declining. In statistical terms, gastric cancer is therefore the most formidable of cancer types, and its control is a pressing issue. Recent evidence indicates that the conversion of normal cells to so-called "clinical cancer" is the prerequisite for a multistage process which is intimately associated with an accumulation of multiple gene alterations including both oncogenes and tumor-suppressor genes. Gastric cancer is no exception, in that it reveals multiple gene changes whose scenario differs, depending on their ...
Surgical Treatment of Bronchial Carcinoma
If a consecutive series of patients with lung cancer is followed up until the decision is made about therapy, it emerges that the role of surgery is quite small. Only a very limited proportion will ultimate ly qualify for rationally conceived surgical therapy; most patients are inoperable. In a series of 397 patients investigated at our hospi tal, 78% were inoperable on the basis of preoperative evaluation and a further 3% proved nonresectable at thoracotomy; therefore, only 19% were suitable for resection. On the other hand, surgery is still thought to offer the best, if not the only realistic chance of cure. The question "operable or not?" is therefore of vital importance for the individua...
Management of Gastric Cancer
Gastric cancer has been one of the great malignant scourges affecting man kind for as long as medical records have been kept. Until operative resection pioneered by Bilroth and others became available, no effective treatment was feasible and death from cancer was virtually inevitable. Even with resection by total gastrectomy, the chances of tumor eradication remained small. Over recent years, however, the situation has been changing. Some changes have resulted from better understanding of the disease, early detec tion, and better management techniques with applied clinical research, but the reasons for other changes are poorly understood. For example, the incidence of gastric cancer is decre...
Antacids and Anti Reflux Agents
This book provides a comprehensive examination of antacids, their related formulations, and alternative medications in the treatment of upper gastrointestinal acidity. Topics discussed include the physicochemical properties of antacids and their evaluation in vivo and in vitro, their efficacy in the treatment of gastrointestinal disorders, the relevant physiology of the upper gastrointestinal tract, the disadvantages of antacids, and the behavior and uses of anti-reflux agents. The book emphasizes the importance of both pharmaceutics and physiology in the behavior of antacids and their efficacy. Over 2000 references to research are provided, making Antacids and Anti-Reflux Agents an essential reference volume for all clinicians involved in the treatment of disorders of the upper gastrointestinal tract, as well as for pharmacologists and pharmaceutical scientists.
