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Gastric cancer has been one of the great malignant scourges affecting man kind for as long as medical records have been kept. Until operative resection pioneered by Bilroth and others became available, no effective treatment was feasible and death from cancer was virtually inevitable. Even with resection by total gastrectomy, the chances of tumor eradication remained small. Over recent years, however, the situation has been changing. Some changes have resulted from better understanding of the disease, early detec tion, and better management techniques with applied clinical research, but the reasons for other changes are poorly understood. For example, the incidence of gastric cancer is decre...
This book is written as a comprehensive guide for residents and young orthopaedic surgeons embarking on research, especially for those doing so for the very first time. It is specially designed to cater to the needs of trainees in the region preparing their theses for masters or fellowship degrees in orthopaedic surgery.It provides a detailed insight on the importance of strategic planning, organisational ability, resourcefulness, innovativeness and creativity to produce good research. Even more crucial is the necessity to have dedication, perseverance and strong commitment to pursue research. Infra-structural, technical, manpower and funding support are equally important. It describes how t...
In this book we examined a periprocedural complication of coronary angiography, and coronary intervention. That includes related to cardiac catheterization and diagnostic coronary angiography, and those that occur as a consequence of the specific equipment. However, improvements in devices, the use of stents, and aggressive antiplatelet therapy have significantly reduced the incident of major periprocedural complications. This book giving knowledge and experiences many of interventional cardiologists from all over the world, and provide possibility to recognize new approach in this domain. Book gives lecture on how we image and how we decide on what to treat, how to treat it, and then results of that treatment. They offer many answers to what we have today and what we will have tomorrow.
In contrast to the continuously increasing success in kidney, liver, heart, and pancreas transplantation, small-bowel transplantation has not shown simi larly impressive progress until recently. The few clinical attempts at small-intestinal transplantation in the late 1960s and early 1970s were unsuccessful. In spite of these initial failures, a few groups of surgeons continued to investigate the problems of small-bowel transplantation from the technical, functional, and immunologic point of view. Now, about 15 years later, conditions have changed. Total parenteral nutrition has made tremendous progress, thus maintaining patients with short-bowel syndrome who are potential recipients of smal...
The introduction of laparoscopic cholecystectomy (LC) revolutionized gallstone surgery because of the reduced operative trauma, quicker recovery time and diminished postoperative pain. More than 80% of all elective cholecystectomies are now performed laparoscopically. This new procedure, however, is the first in surgical history to have been declared the best option without the prior back-up of comparative scientific data. This volume brings together leading specialists to evaluate 5 years’ experience with LC and to determine whether this procedure can now really be considered the standard treatment for symptomatic gallstones. Following a short historical sketch and discussion of the pathogenesis of gallstone disease, the advantages and disadvantages of conventional open and laparoscopic procedures are considered and international results are compared. The place of conservative treatments using drug therapy and lithotripsy are included to provide complete coverage.
How could one define health and disease? On what presuppositions, and ought we look for such definitions? Does quality of life inherit a subjective or objective evaluation? Are health and quality of life culture dependent concepts? Under the conditions of technologically advanced medicine and the common tendency towards a hedonistic lifestyle such questions come into focus. Hence, one question is of special relevance: which role does health play in our quality of life? The contributions of this interdisciplinary volume aim at the clarification of the various concepts in use. International scholars and scientists outline the framework for a more comprehensive and demanding concept of health and quality of life including philosophical and cultural aspects as well as medical and psychological dimensions.
For many years, arteriogenesis, also called collateral formation, has been regarded as being a beneficial process to restore blood flow to distal tissues in occluded arteries. Therefore, it is frequently referred to in relation to therapeutic angiogenesis. Despite the big clinical potential and the many promising clinical trials on arteriogenesis and therapeutic angiogenesis, the exact molecular mechanisms involved in the multifactorial processes of arteriogenesis are still not completely understood. A better understanding is needed in order to define successful clinical therapies. In this Special Issue, multiple aspects of arteriogenesis and therapeutic angiogenesis will be addressed, rangi...
Scientific knowledge may be communicated in the written form or orally. Written communication (medical writing) usually takes the form of original or research papers, which appear in scientific journals. Oral communication in medicine is usually made during a meeting and is often called a free paper. Oral medical communication abides by certain rules. The objectives of this book are to examine and discuss these rules. Oral medical communication involves taking the floor to speak, whether it be as a speaker, the person who gives the talk in front of an audience, or as part of the audience, who can then ask questions or make comments. The go between is called the moderator. Some forms of oral communication are more specific to meetings with a large audience: free papers, panel discussions or roundtables, posters, and videos. Others are more characteristic of smaller audiences: hospital staff meet ings, or literature update sessions. Educational talks have a didactic goal and resemble a lecture, for instance, in a course, or are closer to a case report, when they are given during a small class get-together.
Contents: V. Zingel, C. Leschke and W. Schunack: Developments in research on histamine (H1) receptor agonists / P.D. Hoeprich: Antifungal chemotherapy / G. de Stevens: The diversity of heterocyclic compounds and their biological activities / R.M. Schultz: Newer antifolate compounds in cancer therapy / P.K. Mehrotra, S. Batra and A.P. Bhadun: Non-steroidal agents for regulation of the menstrual cycle / A.K. Saxena and M. Saxena: Developments in anti-convulsant drugs
The problem of gastric cancer, with its multifaceted aspects, offers an example of diversified oncological research, which includes epidemiology, pathogenesis, histo morphology, surgical and conservative therapy in its spectrum. This disease not only constitutes an interesting and important subject for research, but it is also a challenge for the practitioner due to its inordinately poor prognosis. It therefore appeared a rewarding task to the editors to collect information from individual experts, in order to gain a topical summary of the problems pertaining to gastric cancer, as well as to provide a survey of the progress and the therapeutic possibilities in this field. This task was parti...