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Ch. 1. The discovery of insulin / Robert Tattersall -- ch. 2. The discovery of the cure for pernicious anaemia, vitamin B12 / A. Victor Hoffbrand -- ch. 3. The discovery of penicillin / Eric Sidebottom -- ch. 4. The introduction of cardiac catheterisation / Tony Seed -- ch. 5. The discovery of the structure of DNA / James Scott and Gilbert Thompson -- ch. 6. The interpretation of the genetic code / John MacDermot and Ellis Kempner -- ch. 7. The discovery of neuropeptides and radioimmunoassay of peptide hormones / Jaimini Cegla and Stephen Bloom -- ch. 8. The development of computer-assisted tomography / Adrian M.K. Thomas -- ch. 9. The discovery of prostaglandins / Rod Flower -- ch. 10. The ...
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This richly illustrated book presents in detail the sanctuaries built during the reign of Antiochus I of Commagene (ca. 75-36 BCE), including the three large tombs and ten cult places, and discusses Antiochus’ rule in the context of his religious program and cult of the divine ruler. This book is the final publication of the results of the International Nemrud Daği Project 2001–2003.
This new edition is an extensive treatise on the rationale of limiting dilution analysis (LDA). LDA has evolved from its previous role as a basic research laboratory tool in virology and immunology to one pertaining to many different research disciplines and to clinical applications. Newmethodologies (such as PCR, confocal microscopy, in situ hybridisation) have emerged, with the result that single-cell assays can now be performed on a more defined basis, and the quantitation of cells and their precursors is now more accessible to the limiting dilution approach. This book includesboth detailed mathematical derivations and methodological descriptions so that the uninitiated scientist can set ...
This volume gives an overview on the progress in immune synapse research, from basic science to clinical trials, and the major mechanisms involved. It discusses how interfering with T cell activation may lead to immune tolerance, immune modulation, and the recruitment of regulatory T cells; the role of monoclonal antibodies in tolerance induction; and mechanisms maintaining dominant tolerance.