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Cancer Genetics and Genomics for Personalized Medicine
This book covers almost all fields of cancer genetics and genomics for personalized medicine. Targeted therapy, or precision medicine, or personalized medicine is becoming a standard treatment for many diseases, including cancer. However, how much do we know about the personalized medicine approach? This lucid book helps undergraduate and graduate students, professional researchers, and clinicians to better understand the key concept of personalized medicine. The most up-to-date topics on personalized medicine in this book cover the recent trends in and updates on lung, gastric, liver, breast, and other types of cancers. Circulating tumor cell, cell-free circulating DNA, and microRNAs are di...
North Korea Handbook
This is a timely and comprehensive guide to one of the most volatile, misunderstood, and potentially dangerous states in the world, and one of great strategic importance to U.S. interests in Asia. Featuring a detailed "who's who" section, it covers politics, the economy, the military, education, and culture, and provides numerous vital statistical data.
Companion Diagnostics (CDx) in Precision Medicine
There is a new trend in anti-cancer therapeutics development: a targeted therapy and precision medicine that targets a subgroup of patients with specific biomarkers. An in vitro diagnostic (IVD) assay is required to identify a subgroup of cancer patients who would benefit from the targeted therapy, or not likely benefit, or have a high risk of side effects from the specific drug treatment. This IVD or medical device is called a companion diagnostic (CDx) assay. It is key to have a robust CDx assay or device for the success of targeted therapy and precision medicine. This book covers the technical, historical, clinical, and regulatory aspects of CDx in precision medicine. Clearly, more and more newly developed oncology drugs will require accompanying CDx assays, and this book, with chapters contributed by renowned oncologists, provides a comprehensive foundation for the knowledge and application of CDx for precision medicine.
Criminal Sovereignty
North Korea's criminal conduct, smuggling, trafficking, and counterfeiting, is well known, but the organization directing it is understudied or overlooked. North Korea practices a form of "criminal sovereignty" that is unique in the contemporary international security arena. It uses state sovereignty to protect itself from external interference in its domestic affairs while dedicating a portion of its government to carrying out illicit international activities in defiance of international law and the domestic laws of numerous other nations. The proceeds of these activities are used in a number of ways to sustain North Korea's existence and to enable other policies. The authors of this monograph focus on North Korea's Office #39 as the state apparatus that directs illicit activities to include the manufacture and distribution of illegal drugs, the counterfeiting of U.S. currency, and the manufacture and distribution of counterfeit cigarettes. Finally, as Kim Jong-Il becomes more frail, the authors assess how his successor may continue or alter Office #39's activities.--
Power and the Elite in North Korea
This book explores how political power has shaped the elite and their development in North Korea by examining changes of the elite, their interactions, and specific elite figures, based on the transformation of the power structure and characteristics of the North Korean regime since August 1945. As a socialist state where the party guides the state, the ruling core is the party cadre in North Korea. This book distinguishes the development of the North Korean power into five periods: power structuration of the Soviet forces (1945 to the late 1940s), socialist oligarchic power (late 1940s to mid-1950s), limited personal power (mid-1950s to late 1960s), personal power (late 1960s to mid-1970s) ...
Two-Dimensional Materials for Electromagnetic Shielding
Two-Dimensional Materials for Electromagnetic Shielding Discover a cutting-edge reference on 2D EMI shielding materials for both industrial and academic audiences Two-Dimensional Materials for Electromagnetic Shielding delivers a thorough and comprehensive examination of all aspects of electromagnetic interference (EMI) shielding and microwave absorption, including fundamentals and applications, as well as emerging 2D materials in the field, like graphene, and MXenes. The book covers basic knowledge on shielding mechanisms and the demanding physical, chemical, and mechanical properties of the 2D materials against betrayed electromagnetic waves. The benefits of novel 2D materials over existin...
Leader Symbols and Personality Cult in North Korea
The legitimacy of the North Korean state is based solely on the leaders’ personal legitimacy, and is maintained by the indoctrination of people with leader symbols and the enactment of leadership cults in daily life. It can thus be dubbed a "leader state". The frequency of leader symbols and the richness and scale of leader-symbol-making in North Korea are simply unrivalled. Furthermore, the personality cults of North Korean leaders are central to people’s daily activity, critically affecting their minds and emotions. Both leader symbols and cult activities are profoundly entrenched in the institutions and daily life, and if separated and cancelled, the North Korean state would be transf...
Korea Annual 2003
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Microarray Innovations
In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarr
Advances in Medical Imaging, Detection, and Diagnosis
Medical care is the most critical issue of our time and will be so for the foreseeable future. In this regard, the pace and sophistication of advances in medicine in the past two decades have been truly breathtaking. This has necessitated a growing need for comprehensive reference resources that highlight current issues in specific sectors of medicine. Keeping this in mind, each volume in the Current Issues in Medicine series is a stand‐alone text that provides a broad survey of various important topics in a focused area of medicine—all accomplished in a user-friendly yet interconnected format. This volume addresses advances in medical imaging, detection, and diagnostic technologies. Tec...
