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Advances in Locally Delivered Antimicrobials for Periodontitis Treatment
Periodontal disease represents an inflammatory disease of the tissues supporting the maintenance and functionality of the teeth on the dental arches. The main cause of periodontitis consists in periodontal dysbiosis, which will trigger an inflammatory response, progressively leading to periodontal tissue breakdown. Scaling and root planing represent the gold standard in treating periodontal diseases but, as it was already established, these measures are unable to completely eliminate the subgingival bacterial plaque. Therefore, new adjunctive therapies have emerged, involving systemic and local delivery of various antimicrobial products. This chapter aims to provide current knowledge on the local application of different periodontal supplementary therapies. The chapter focuses on local forms of antimicrobials, such as irrigations, gels or controlled release systems but also on laser/LED-assisted periodontal pocket photodynamic antibacterial therapy (PDT), along with various photosensitizers. Moreover, we present data from current guidelines regarding the recommendations for the main locally delivered antimicrobials.
The Complex Relationship of Periodontal Disease and Rheumatoid Arthritis
The relationship between periodontitis and systemic diseases is an important part of clinical periodontal research, which has been growing steadily. Even though the etiologies of periodontal disease and rheumatoid arthritis (RA) differ, these pathologies have many common features, both being multifactorial diseases characterized by localized chronic inflammatory reactions, which are fuelled by an analogous set of cytokines (among many, the most prominent being Tumour Necrosis Factor (TNF), Interleukin (IL) 6 and 17), leading to high systemic circulating concentrations of inflammatory markers such as C-reactive protein (CRP). It was not until the discovery of peptidylarginine deiminase (PAD) ...
The Role of Osteoporosis as a Systemic Risk Factor for Periodontal Disease
Periodontal disease is an infectious and inflammatory disease with a high incidence in the global population and an extremely complex etiopathogenesis. Osteoporosis is one of the systemic diseases that can affect the integrity of periodontal tissues. Osteoporosis, as a skeletal disease, causes a reduction in bone mass and microarchitectural changes in the bone. Discussions about the connection between the two diseases affecting the bone began in 1960, but, contrary to the high number of studies, discoveries are still being made regarding the pathophysiological mechanisms that link the two diseases. The chapter proposes a systematized description of data on the influence of osteoporotic disease on the periodontal structures, therapeutic methods to address the patient with periodontal disease and osteoporosis and data on the potential influence of conventional and adjunctive periodontal treatment on systemic parameters in patients with osteoporosis.
Periodontology
This Edited Volume Periodontology - Fundamentals and Clinical Features is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field. The book comprises single chapters authored by various researchers and edited by an expert active in the dental medicine research area. All chapters are complete in themselves but united under a common research study topic. This publication aims at providing a thorough overview of the latest research efforts by international authors in periodontology, and opening new possible research paths for further novel developments.
Human Amniotic Membrane: Basic Science And Clinical Application
This book is a comprehensive guide for all tissue bank operators to screen, procure and process amniotic membrane for clinical application.The amnion comes close to being the ideal biological membrane or dressing — readily available, inexpensive to procure and process. Its basic science is discussed in detail — anatomy, biological and biomechanical properties.It can be procured from the placenta in normal vaginal deliveries and from Caesarean Sections. Processing is by freeze-drying or by air-drying process with sterilisation using gamma irradiation.The product has low antigenicity, has anti-microbial properties with ability to enhance epithelisation with marked relief of pain. It is useful as a dressing for wounds — flap wounds, burn wounds, injury wounds, diabetic ulcers, leprous ulcers and post-surgery wounds and post-radiation wounds. It is also used as a biological scaffold for cells in tissue engineering. Its ophthalmic applications include treatment of corneal ulcers and conjunctival tumours. Oral uses include gingiva depigmentation and periodontal regeneration.
Electrospun Materials and Their Allied Applications
The aim of this book is to explore the history, fundamentals, manufacturing processes, optimization parameters, and applications of electrospun materials. The book includes various types of electrospun materials such as antimicrobial, smart, bioinspired systems. It focuses on the many application areas for electrospun materials such as energy storage and harvesting, catalysis, biomedical including gene delivery and tissue engineering, separation, adsorption and water treatment technologies, packaging. The book emphasizes the enhanced sustainable properties of electrospun materials, with the challenges and future developments being discussed in detail. The chapters are written by top-class researchers and experts from throughout the world.
Recent Advances in Bone Tumours and Osteoarthritis
This book is a combination of recent advances in two major areas of orthopaedics: Bone tumours and Osteoarthritis. All chapters are contributed by well-known researchers and surgeons in Orthopaedics working across the globe. The book is divided into two major parts for clarity. All authors have contributed their original research, their experience in the field, and the recent advances that will keep the reader well informed and up to date in our understanding of bone tumours and osteoarthritis. This is a 'must have' reference book for any medical library or an individual who is keen to update and have CME (continuous medical education) points added to their learning.
Carranza's Clinical Periodontology
This new, updated edition of CARRANZA'S CLINICAL PERIODONTOLOGY is the most comprehensive and authoritative resource in periodontics available today. Beautifully illustrated, it describes clinical aspects of modern periodontology balanced by detailed presentations of the fundamental basis of anatomy, physiology, etiology, and pathology. Discussions of the interrelationships between periodontal and restorative dental therapies set it apart from other books. The 9th Edition features a new 2-color format, 32 pages of full-color photos, and 6 new chapters that feature the latest advances in technology, including the use of digital imaging, dental implants, and changes in surgical techniques. A NEW companion CD-ROM showcases 750 clinical images in full color and provides review material to strengthen the user's diagnostic, treatment planning, and treatment skills.
Engineered Antimicrobial Surfaces
This volume looks at the different aspects involved in controlling microbial growth and the techniques employed in obtaining sterile surfaces. It covers research on coatings, nano-materials, herbal materials, naturally occurring antimicrobials in designing antimicrobial surfaces. It discusses issues of antibiotic resistance, synthesis techniques, toxicity, and current and potential applications of antimicrobial surfaces, and this book will serve as a useful reference to a broad range of scientists, industrial practitioners, graduate and undergraduate students, and other professionals in the fields of polymer science and engineering, materials science, surface science, bioengineering and chemical engineering.
Frontiers in Guided Wave Optics and Optoelectronics
As the editor, I feel extremely happy to present to the readers such a rich collection of chapters authored/co-authored by a large number of experts from around the world covering the broad field of guided wave optics and optoelectronics. Most of the chapters are state-of-the-art on respective topics or areas that are emerging. Several authors narrated technological challenges in a lucid manner, which was possible because of individual expertise of the authors in their own subject specialties. I have no doubt that this book will be useful to graduate students, teachers, researchers, and practicing engineers and technologists and that they would love to have it on their book shelves for ready reference at any time.
