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Molecular Biology and Toxicology of Metals provides a critical review and analysis of the current state of knowledge of metal ion transport and metabolism in prokaryotic and eukaryotic cellular systems. It covers the latest information on specific metals and the biological molecules with which metals interact. It also details mechanisms in the handling and toxicity of metals in specific organ systems, and the role of metals in cell signalling and gene transcription in target cells. This book is sure to prove a fertile meeting ground for the disciplines of molecular genetics and metal toxicology.
The principles of environmental toxicology are clearly presented here for university students and professionals in related fields. The book explains basic concepts such as the fate of toxic chemicals in the body, then goes on to discuss specific environmental problems.
Safety in the process industries is critical for those who work with chemicals and hazardous substances or processes. The field of loss prevention is, and continues to be, of supreme importance to countless companies, municipalities and governments around the world, and Lees’ is a detailed reference to defending against hazards. Recognized as the standard work for chemical and process engineering safety professionals, it provides the most complete collection of information on the theory, practice, design elements, equipment, regulations and laws covering the field of process safety. An entire library of alternative books (and cross-referencing systems) would be needed to replace or improve...
This volume contains the Proceedings of the International Conference on Simulation of Semiconductor Devices and Processes, SISPAD 01, held on September 5–7, 2001, in Athens. The conference provided an open forum for the presentation of the latest results and trends in process and device simulation. The trend towards shrinking device dimensions and increasing complexity in process technology demands the continuous development of advanced models describing basic physical phenomena involved. New simulation tools are developed to complete the hierarchy in the Technology Computer Aided Design simulation chain between microscopic and macroscopic approaches. The conference program featured 8 invited papers, 60 papers for oral presentation and 34 papers for poster presentation, selected from a total of 165 abstracts from 30 countries around the world. These papers disclose new and interesting concepts for simulating processes and devices.
Chapters 3 to 5 give an account of bacterial MTs, MTs in yeast and fungi, and MTs in plants. Most astonishingly, the MTs of bacteria and plants contain next to cysteine also histidine residues and thus, metal ions are not only sulfur- but also imidazole-coordinated which gives rise to zinc finger-like structures. Remarkably, yeast and fungal MTs are Cu(I) rather than Zn(II) or Cd(II) binding proteins. Next, Chapters 6 through 9 discuss the MTs of dipteran insects, including the model organism Drosophila melanogaster, earthworms and nematodes, as well as echinoderms, crustaceans, molluscs, and fish. Actually, aquatic animals, both vertebrates and invertebrates, have the potential to be used f...
This volume offers the most comprehensive presentation available on metal toxicology. It discusses not only metals but also the toxic endpoints, such as neurotoxicity, renal toxicity, and cancer induction. Chapters are written by experts in their respective fields, focusing on carcinogenesis and human exposures and highlighting the major aspects and issues of toxicity in general.