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Bacterial Pathogenesis
This detailed volume presents a diverse set of methodological approaches designed to improve our understanding of bacterial infections from a wide range of bacterial species. Beginning with biofilms and subcellular compartments, the book explores transcriptional analysis, methods for studying plasmid dynamics, and tools for phylogenetic analysis of bacterial genomes, as well as bacterial effector proteins interfering with host systems, host response analysis, and in vivo and in vitro infection models. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Bacterial Pathogenesis: Methods and Protocols, Second Edition is a vital resource for researchers in the area of infection biology, as well as but not limited to, those working in the fields of microbiology, immunology, structural biology, molecular biology, genetics, imaging, and computational study.
Group A Streptococcus
This volume details Group A Streptococcus (GAS) research and provides the reader with an extensive collection of research protocols within this important field. Chapters guide readers through standard genetic protocols such as whole genome sequencing, transcriptome analyses, proteome analysis, application of GAS-derived molecular tools, and methods that are crucial for the evaluation of novel GAS vaccines and GAS virulence factors, including bactericidal assays and animal infection models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Group A Streptococcus: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Applied Degree Education and the Shape of Things to Come
This edited book seeks to evolve a global community of practice to share case studies, engage in critical discussion and spearhead thought leadership, to address the paradigm shift in next generation educational practice. This book showcases novel research studies in various forms and engenders interdisciplinary conversation and exchange concerning innovation, technology, and the role of applied education in workforce futures. It also equips readers with global perspectives on the latest developments in applied degree education and thinking on new education futures.
Disinformation and Fake News
This book is a collection of chapters penned by practitioners from around the world on the impact that disinformation and fake news has had in both the online and social sphere. While much has been said about individual disinformation campaigns in specific countries, this book offers a panoramic view of how these campaigns are conducted, who they target, and how they are spread. By bringing together research on specific countries and international data mined from questionnaires and online studies, the understanding of the term 'fake news' is greatly expanded and the issues we face are brought to light. The book includes contributions by experts such as Jean-Baptiste Vilmer (Macron Leaks), and includes case studies from Asia, such as Singapore and Myanmar, written in an accessible manner for the general interested reader, practitioners and policymakers in the field.
Figures of Southeast Asian Modernity
We live in a world populated not just by individuals but by figures, those larger-than-life people who in some way express and challenge our conventional understandings of social types. This innovative and collaborative work takes up the wide range of figures that populate the social and cultural imaginaries of contemporary Southeast Asia—some familiar only in specific places, others recognizable across the region and even globally. It puts forward a series of ethnographic portraits of figures that represent and give voice to something larger than themselves, offering a view into social life that is at once highly particular and general. They include the Muslim Television Preacher in Indon...
Strain Variation in the Mycobacterium tuberculosis Complex: Its Role in Biology, Epidemiology and Control
Until about 10 years ago, the general view in the field was that Mycobacterium tuberculosis, the causative agent of human tuberculosis was a “clone” with insufficient natural sequence variation between clinical strains to be considered biologically and epidemiologically “relevant”. This view has now changed quite dramatically thanks to the –omics revolution, particularly the advent of next generation DNA sequencing. Large-scale comparative genomic studies over the last few years have revealed that M. tuberculosis clinical strains are more genetically diverse than appreciated previously. Moreover, an increasing number of experimental and epidemiological studies are showing that this...
Kin Recognition in Protists and Other Microbes
Kin Recognition in Protists and Other Microbes is the first volume dedicated entirely to the genetics, evolution and behavior of cells capable of discriminating and recognizing taxa (other species), clones (other cell lines) and kin (as per gradual genetic proximity). It covers the advent of microbial models in the field of kin recognition; the polymorphisms of green-beard genes in social amebas, yeast and soil bacteria; the potential that unicells have to learn phenotypic cues for recognition; the role of clonality and kinship in pathogenicity (dysentery, malaria, sleeping sickness and Chagas); the social and spatial structure of microbes and their biogeography; and the relevance of unicells’ cooperation, sociality and cheating for our understanding of the origins of multicellularity. Offering over 200 figures and diagrams, this work will appeal to a broad audience, including researchers in academia, postdoctoral fellows, graduate students and research undergraduates. Science writers and college educators will also find it informative and practical for teaching.
The Oxford Handbook of Food Ethics
Academic food ethics incorporates work from philosophy but also anthropology, economics, the environmental sciences and other natural sciences, geography, law, and sociology. Scholars from these fields have been producing work for decades on the food system, and on ethical, social, and policy issues connected to the food system. Yet in the last several years, there has been a notable increase in philosophical work on these issues-work that draws on multiple literatures within practical ethics, normative ethics and political philosophy. This handbook provides a sample of that philosophical work across multiple areas of food ethics: conventional agriculture and alternatives to it; animals; consumption; food justice; food politics; food workers; and, food and identity.
