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Developing Fluent Readers
  • Language: en
  • Pages: 162

Developing Fluent Readers

Viewing fluency as a bridge between foundational skills and open-ended learning, this book guides teachers through effective instruction and assessment of fluent reading skills in the primary grades. Fluency?s relationship to phonological awareness, phonics, and print concepts is explained, and practical methods are shared for integrating fluency instruction in a literacy curriculum grounded in the Common Core State Standards (CCSS). Classroom examples, weekly lesson plans, and extensive lists of recommended texts add to the book?s utility for teachers.

Apoptosis, Senescence and Cancer
  • Language: en
  • Pages: 596

Apoptosis, Senescence and Cancer

This book provides insight into established practices and research into apoptosis and senescence. The volume thoroughly examines novel and emerging techniques and research in the fields of cell death pathways, senescence growth arrest, drugs and resistance, DNA damage response, and other topics that still hold mysteries for researchers. In total, this volume provides basic scientists and clinicians with a deeper and more complete understanding of the cellular responses of malignancies which may determine the effectiveness of treatment, both in the initial stages of the disease as well as in disease recurrence.

A Houghton Library Chronicle, 1942-1992
  • Language: en
  • Pages: 124

A Houghton Library Chronicle, 1942-1992

  • Categories: Art

Harvard's home for rare books and manuscripts opened in 1942, and thanks to the energy of a small group of librarians and the creativity and generosity of its benefactor, Arthur Houghton, it quickly emerged as a center of inquiry and memory without equal. This 1992 volume, compiled by senior Houghton librarians, blends documentary with oral history to look back on the library's origins, the growth of its collections, and the activities of the staff who made it a home for precious books and original scholarship.

Antibody Therapeutics
  • Language: en
  • Pages: 385

Antibody Therapeutics

  • Type: Book
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  • Published: 2019-10-10
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  • Publisher: CRC Press

Published in 1997: Antibody Therapeutics is a comprehensive evaluation of progress toward using humanized antibodies as a new generation of therapeutics. The humanized antibodies that have led the way in product approval are discussed as case studies, offering an insight into the preclinical and clinical data acquired during the regulatory approval process. Leading experts offer their findings as examples of what works and what does not, saving you time and making your research more cost effective. This book is essential reading for researchers, clinicians, development and regulatory staff in pharmaceutical and biotechnology companies, and hospital staff, including policy and decision makers. It also provides postgraduate and medical students with an authoritative overview of the field.

Chemical and Structural Approaches to Rational Drug Design
  • Language: en
  • Pages: 298

Chemical and Structural Approaches to Rational Drug Design

  • Type: Book
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  • Published: 2020-12-18
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  • Publisher: CRC Press

This book is the first to provide both a broad overview of the current methodologies being applied to drug design and in-depth analyses of progress in specific fields. It details state-of-the-art approaches to pharmaceutical development currently used by some of the world's foremost laboratories. The book features contributors from a variety of fields, new techniques, previously unpublished data, and extensive reference lists.

Manual of Immunological Methods
  • Language: en
  • Pages: 152

Manual of Immunological Methods

  • Type: Book
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  • Published: 2021-09-01
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  • Publisher: CRC Press

The Manual of Immunological Methods represents the collaboration of the Canadian Network of Toxicology Centers, a non-profit network of university-based scientists dedicated to research, training, risk assessment, and communication. This manual provides detailed immunological methods that can be utilized by researchers or practitioners who want to

Human Growth Hormone Pharmacology
  • Language: en
  • Pages: 196

Human Growth Hormone Pharmacology

  • Type: Book
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  • Published: 1995-03-09
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  • Publisher: CRC Press

This book addresses a wide range of basic and clinical issues in the physiology and pharmacology of growth hormone. The volume is organized like a textbook. It begins with factors contributing to GH gene expression, the functional relationships of the GH receptor, molecular biological analysis of the GH-GH receptor complex and proceeds to describe the insulin-like growth factor axis. Transgenic models are discussed for analysis of discrete effects. These discussions provide a bridge to clinically oriented discussions of growth abnormalities in GH deficient children, GH insensitivity due to deficiency of the GH receptor, and the concept of aging as a GH/IGF-I deficiency state. Discussions also include the immune system as a source and a responder to GH, GHRH, IGF-I and the effects of GH excess.

Cancer Treatment Reports
  • Language: en
  • Pages: 616

Cancer Treatment Reports

  • Type: Book
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  • Published: 1983
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  • Publisher: Unknown

None

Pharmacology of Antimuscarinic Agents
  • Language: en
  • Pages: 526

Pharmacology of Antimuscarinic Agents

  • Type: Book
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  • Published: 1997-11-25
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  • Publisher: CRC Press

The theoretical and practical significance of antimuscarinic drugs is more obvious today than ever before. Antimuscarinics have helped to explore the pathomechanisms of of Alzheimer's disease, and to treat the symptoms of Parkinson's, cardiovascular problems, gastrointestinal diseases, and even nerve gas poisoning. No other drug class can claim as long a history with so many therapeutic applications, yet the most significant developments in this broad chapter of pharmacology come from the discovery of different muscarinic receptor sites in the peripheral and central nervous system and from the availability of many new selective agents, notably antagonists, for these different receptor types. Pharmacology of Antimuscarinic Agents, written by an expert in anesthesiology and drug research, focuses on the basic principles of antimuscarinic drugs, their therapeutic value, how they work, and what versions are now available in the U.S. and abroad. This is the first time in decades an author has reviewed historical and current literature to present a comprehensive, standard reference on the antimuscarinic family.

Angiotensin II Receptors
  • Language: en
  • Pages: 190

Angiotensin II Receptors

  • Type: Book
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  • Published: 1994-07-13
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  • Publisher: CRC Press

This unique reference set provides a broad-based, in-depth presentation on angiotensin II receptors, from the genes that encode them to the responses they mediate in humans. The books emphasize known and potential therapeutic applications of the antagonists of angiotensin II receptors and the angiotensin-converting enzyme inhibitors. The molecular biology of angiotensin II receptors is reviewed, as are the biochemical effects mediated by angiotensin II receptors. This is the first publication to analyze in detail the structure-activity relationships for both peptide and nonpeptide angiotensin II receptor agonists and antagonists. It also presents the pharmacological effects mediated by angiotensin II receptors both in the periphery and in the brain.