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Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide
This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)
The Effect
Extensive code examples in R, Stata, and Python Chapters on overlooked topics in econometrics classes: heterogeneous treatment effects, simulation and power analysis, new cutting-edge methods, and uncomfortable ignored assumptions An easy-to-read conversational tone Up-to-date coverage of methods with fast-moving literatures like difference-in-differences
Handbook of Matching and Weighting Adjustments for Causal Inference
An observational study infers the effects caused by a treatment, policy, program, intervention, or exposure in a context in which randomized experimentation is unethical or impractical. One task in an observational study is to adjust for visible pretreatment differences between the treated and control groups. Multivariate matching and weighting are two modern forms of adjustment. This handbook provides a comprehensive survey of the most recent methods of adjustment by matching, weighting, machine learning and their combinations. Three additional chapters introduce the steps from association to causation that follow after adjustments are complete. When used alone, matching and weighting do not use outcome information, so they are part of the design of an observational study. When used in conjunction with models for the outcome, matching and weighting may enhance the robustness of model-based adjustments. The book is for researchers in medicine, economics, public health, psychology, epidemiology, public program evaluation, and statistics who examine evidence of the effects on human beings of treatments, policies or exposures.
From the Shtetl to America
THE JACOB RASSEN STORY Jacob Rassen’s life (1905 – 1986) reflects much of the Jewish history of the twentieth century, from the last years of the Eastern European shtetl to modern America. His life was shaped by four wars: two “local” wars in Lithuania and the two world wars. As a young man, Jacob developed a passion for agronomy. He taught and wrote extensively. As an agronomist, he traveled to Denmark and Russia. He spent a year in Palestine, starting a school of agronomy in the early days of the kibbutz movement. Jacob remained in Europe during World War II. He survived the Dvinsk and Riga ghettos, concentration camps and a year as a partisan fighter. His first wife and two children were killed in 1943 as the Dvinsk ghetto was liquidated. In 1945, Jacob remarried and emigrated to the United States, where he started a new life and family. He lived mostly in Massachusetts and spent his last year in San Francisco. Jacob recorded a nine-hour narrative in 1986. The transcript captures his gift for storytelling, his passion for life, and his remarkable tale of survival.
The Freedom of Peaceful Action
The Freedom of Peaceful Action is the first installment of the trilogy The Nature of Liberty, which makes an ethical philosophic case for individual liberty and the free market against calls for greater government regulation and control. The trilogy makes a purely secular and nonreligious ethical case for the individual’s rights to life, liberty, private property, and the pursuit of happiness as championed by the U.S. Founding Fathers. Inspired by such philosophic defenders of free enterprise as John Locke, Herbert Spencer, and Ayn Rand, The Nature of Liberty shows that such individual rights are not imaginary or simply assertions, but are institutions of great practical value, making pros...
Berkeley DB
Small, special-purpose computing devices and high-end core Internet servers need fast, reliable database management. Berkeley DB is an embedded database that provides high-performance, scalable, transaction-protected and recoverable data management services to applications. Extremely portable, this library runs under almost all UNIX and Windows variants, as well as a number of embedded, real-time operating systems. Berkeley DB is the ultimate resource for the world's most widely deployed embedded database engine. This book will aid software architects and engineers, product managers, and systems and network administrators without the overhead imposed by other database products. Designed by p...
