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Hot Isostatic Pressing
The book presents recent advances in the use of hot isostatic pressing (HIP) techniques in the manufacture and processing of materials. Keywords: Turbomachinery, Heat Exchangers, Hydrogen Electrolyzers, Duplex Stainless Steels, Naval Nuclear Applications, Rapid L-PBF Printing, Combined Manufacturing and Heat Treatment, Nickel-Based Alloy, Magnetically Soft FeSi6.5 Powder, GH4169 Superalloy, Additive Manufacturing, Tungsten Alloy, Three-Dimensional Flow Path Structure, Accident Tolerant Fuel Cladding, Simulation-Based Manufacturing, Modelling of Powder Filling, Capsule Filling, Porous Materials, Large Complex Shape Parts, Shear Stress Coefficient, Capsule Material Strain Hardening.
Powder Flow
Powder flow has attracted increased attention in recent years. This book stands out by not only providing the reader with guidance on what to measure but also how to interpret results.
Silos
Bringing together the leading European expertise in behaviour and design of silos, this important new book is an essential reference source for all concerned with current problems and developments in silo technology. Silos are used in an enormous range of industries and the handling characteristics of many industrial materials require different approaches for successful, economical installations. For the first time, the many approaches taken by specialists in different fields are brought together in a unified way so that common problems can be addressed. This book is the result of a four-year European project - Concerted Action - Silos - funded under the Brite Euram programme which has involved over 100 expert engineers and researchers from all over Europe, in seven working groups.
Intelligent Computing and Optimization
This book of Springer Nature is another proof of Springer’s outstanding greatness on the lively interface of Holistic Computational Optimization, Green IoTs, Smart Modeling, and Deep Learning! It is a masterpiece of what our community of academics and experts can provide when an interconnected approach of joint, mutual, and meta-learning is supported by advanced operational research and experience of the World-Leader Springer Nature! The 6th edition of International Conference on Intelligent Computing and Optimization took place at G Hua Hin Resort & Mall on April 27–28, 2023, with tremendous support from the global research scholars across the planet. Objective is to celebrate “Research Novelty with Compassion and Wisdom” with researchers, scholars, experts, and investigators in Intelligent Computing and Optimization across the globe, to share knowledge, experience, and innovation—a marvelous opportunity for discourse and mutuality by novel research, invention, and creativity. This proceedings book of the 6th ICO’2023 is published by Springer Nature—Quality Label of Enlightenment.
Materials Research for Manufacturing
This book is about applied materials research in industry. It presents various important topics and challenges and gives guidance to materials researchers who move to industry. The book focuses on the materials manufacturing issues for industrial application. It deals with developments and challenges in traditional materials areas, such as metals and ceramics, and new opportunities that have risen from nanotechnology and additive manufacturing. The chapters, written by senior people from large companies, include successful manufacturing undertakings, several distinct and unresolved manufacturing challenges, with the focus on approaches, timelines and the skills needed for future company research and development. The book provides a cross-section of current and future approaches valuable for new employees and academics working in industry.
The Neurodegeneration Revolution
The Neurodegeneration Revolution: Emerging Therapies and Sustainable Solutions provides insights into the mechanics, characteristics, behavior, application, and manufacturing of advanced materials such as nanowires, 2D materials, biomaterials, smart materials, and more. The first section discusses the mechanics and electronic and magnetic properties of nanomaterials, photonic, and photonic materials and devices, 2D magnetic materials, smart materials and coatings, metamaterials, and microdevices and sensors. The second section of the book covers manufacturing technologies and methods of previously discussed materials, outlining manufacturing techniques for additive manufacturing of metallic ...
Tumour microenvironment in cancer research and drug discovery
The implication of tumour microenvironment (TME) on cancer progression and therapeutic response has profoundly shifted the paradigms of molecular cancer research and drug discovery. The intricate networks of immune-inflammatory cells and signalling, cancer-associated fibroblasts, endothelial cells and adipose cells are extensively researched for diagnostics, therapeutics and predictive values. This includes siRNA and miRNA nanotherapeutics targeting these molecular components, owing to their powerful gene-silencing properties. Despite the concerted effort in the development of drug targeting TME, such as BLZ945 (a colony-stimulating factor-1 receptor inhibitor), there is a void in clinically satisfactory drug to target this intricate factor, thus far.
Palliative Surgery
Palliative surgery can greatly contribute to improving symptom control and quality of life for terminal cancer patients. Owing to the advanced stage of the disease, however, this type of surgery is also associated with significant morbidity and mortality. It is therefore important for surgeons to have a sound understanding of the medical and scientific background underlying treatment decisions in palliative surgery, a foundation that this book provides. The opening chapters examine the relationship between palliative medicine and palliative surgery and address general issues including pain management and anesthesiological considerations. The role of palliative surgery in a wide range of disease settings is then thoroughly explored, including detailed information on surgical techniques and their indications and outcomes. This book will be an invaluable resource for all who wish to learn more about the emerging role of palliative surgery.
Signal Transduction
This publication focuses on the subject of signal transduction and its role in the pathogenesis and progression of human breast cancer. Within the past 10 years, the explosion in our knowledge of these processes has significantly altered our understanding of breast cancer, and resulted in the first receptor-based therapies. This volume examines a variety of relevant signalling pathways in mammary epithelium and explores their mechanisms and functional contribution to the evolution of this disease. The articles herein explore receptor-based signalling that occurs both at the cell surface and within the nucleus that controls the gene expression required for the breast cancer phenotype. Of course, any good series of reviews should open up more questions than they answer, and the current collection of review provides no exception. It is our desire that the discussions engendered by the reviews herein stimulate additional research on these topics. Clearly, further mechanistic understanding of these underpinnings of breast neoplasia has been and will be the wellspring for novel therapies of this disease.
