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Making Mice
  • Language: en

Making Mice

Making Mice blends scientific biography, institutional history, and cultural history to show how genetically standardized mice came to play a central role in contemporary American biomedical research. Karen Rader introduces us to mouse "fanciers" who bred mice for different characteristics, to scientific entrepreneurs like geneticist C. C. Little, and to the emerging structures of modern biomedical research centered around the National Institutes of Health. Throughout Making Mice, Rader explains how the story of mouse research illuminates our understanding of key issues in the history of science such as the role of model organisms in furthering scientific thought. Ultimately, genetically standardized mice became icons of standardization in biomedicine by successfully negotiating the tension between the natural and the man-made in experimental practice. This book will become a landmark work for its understanding of the cultural and institutional origins of modern biomedical research. It will appeal not only to historians of science but also to biologists and medical researchers.

Gracer Finds a Home
  • Language: en
  • Pages: 30

Gracer Finds a Home

  • Type: Book
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  • Published: 2009-06-22
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  • Publisher: CreateSpace

Gracer is a little gray kitty who is waiting to be born. He is on a quest to discover his own talents and purpose, which he will bring with him to earth. In his exploration, Gracer learns from other animals, and ultimately, must listen to his own inner guidance.This is a charming and delightful story about trusting one's intuition. The book is written for children at the pre-school and early school age level, although it is suitable for children of all ages.

The Life of a Virus
  • Language: en
  • Pages: 422

The Life of a Virus

We normally think of viruses in terms of the devastating diseases they cause, from smallpox to AIDS. But in The Life of a Virus, Angela N. H. Creager introduces us to a plant virus that has taught us much of what we know about all viruses, including the lethal ones, and that also played a crucial role in the development of molecular biology. Focusing on the tobacco mosaic virus (TMV) research conducted in Nobel laureate Wendell Stanley's lab, Creager argues that TMV served as a model system for virology and molecular biology, much as the fruit fly and laboratory mouse have for genetics and cancer research. She examines how the experimental techniques and instruments Stanley and his colleagues developed for studying TMV were generalized not just to other labs working on TMV, but also to research on other diseases such as poliomyelitis and influenza and to studies of genes and cell organelles. The great success of research on TMV also helped justify increased spending on biomedical research in the postwar years (partly through the National Foundation for Infantile Paralysis's March of Dimes)—a funding priority that has continued to this day.

Life on Display
  • Language: en
  • Pages: 482

Life on Display

  • Categories: Art

Life on Display traces the history of biological exhibits in American museums to demonstrate how science museums have shaped and been shaped by understandings of science and public education in twentieth-century society. Karen Rader and Victoria Cain document how public natural history and science museums’ ongoing efforts to create popular educational displays led these institutions to develop new identities, ones that changed their positions in both twentieth-century science and American culture. They describe how, pre-1945, biological exhibitions changed dramatically--from rows upon rows of specimen collections to large-scale dioramas with push-button displays--as museums attempted to ne...

Science and Technology in the Global Cold War
  • Language: en
  • Pages: 467

Science and Technology in the Global Cold War

  • Type: Book
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  • Published: 2014-10-31
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  • Publisher: MIT Press

Investigations of how the global Cold War shaped national scientific and technological practices in fields from biomedicine to rocket science. The Cold War period saw a dramatic expansion of state-funded science and technology research. Government and military patronage shaped Cold War technoscientific practices, imposing methods that were project oriented, team based, and subject to national-security restrictions. These changes affected not just the arms race and the space race but also research in agriculture, biomedicine, computer science, ecology, meteorology, and other fields. This volume examines science and technology in the context of the Cold War, considering whether the new institu...

Experimenting with Humans and Animals
  • Language: en
  • Pages: 217

Experimenting with Humans and Animals

  • Type: Book
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  • Published: 2022-08-02
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  • Publisher: JHU Press

"The author discusses key historical episodes in the use of living beings in experiments in science and medicine. This new edition emphasizes a broader understanding of experimentation and has material on prisoners and slaves as experimental subjects, gene therapy, and self-experimentation"--

Creatures of Cain
  • Language: en
  • Pages: 416

Creatures of Cain

Drawing on a wealth of archival materials and in-depth interviews, Erika Lorraine Milam reveals how the scientists who advanced this "killer ape" theory capitalized on an expanding postwar market in intellectual paperbacks and widespread faith in the power of science to solve humanity's problems, even to answer the most fundamental questions of human identity. The killer ape theory spread quickly from colloquial science publications to late-night television, classrooms, political debates, and Hollywood films. Behind the scenes, however, scientists were sharply divided, their disagreements centering squarely on questions of race and gender. Then, in the 1970s, the theory unraveled altogether when primatologists discovered that chimpanzees also kill members of their own species. While the discovery brought an end to definitions of human exceptionalism delineated by violence, Milam shows how some evolutionists began to argue for a shared chimpanzee-human history of aggression even as other scientists discredited such theories as sloppy popularizations.

A History of Organ Transplantation
  • Language: en
  • Pages: 578

A History of Organ Transplantation

"The first book of its kind, A History of Organ Transplantation examines the evolution of surgical tissue replacement from classical times to the medieval period to the present day. This volume will be useful to undergraduates, graduate students, scholars, surgeons, and the general public. Both Western and non-Western experiences as well as folk practices are included."--Project Muse.

Science and the American Century
  • Language: en
  • Pages: 483

Science and the American Century

The twentieth century was one of astonishing change in science, especially as pursued in the United States. Against a backdrop of dramatic political and economic shifts brought by world wars, intermittent depressions, sporadic and occasionally massive increases in funding, and expanding private patronage, this scientific work fundamentally reshaped everyday life. Science and the American Century offers some of the most significant contributions to the study of the history of science, technology, and medicine during the twentieth century, all drawn from the pages of the journal Isis. Fourteen essays from leading scholars are grouped into three sections, each presented in roughly chronological...

Classical Genetic Research and Its Legacy
  • Language: en
  • Pages: 242

Classical Genetic Research and Its Legacy

  • Type: Book
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  • Published: 2004-10-07
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  • Publisher: Routledge

With the rise of genomics, the life sciences have entered a new era. This book provides a comprehensive history of mapping procedures as they were developed in classical genetics. An accompanying volume - From Molecular Genetics to Genomics - covers the history of molecular genetics and genomics. The book shows that the technology of genetic mapping is by no means a recent acquisition of molecular genetics or even genetic engineering. It demonstrates that the development of mapping technologies has accompanied the rise of modern genetics from its very beginnings. In Section One, Mendelian genetics is set in perspective from the viewpoint of the detection and description of linkage phenomena....