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Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?
Advances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them.
PNF in Practice
The approach here is based on the concepts set out by Dr. Herman Kabat and taught by Margaret Knott, and this second edition adds many new illustrations including demonstrations of the techniques and pictures of actual patient treatment. The gait section has been expanded with an introduction to normal components and photos of patient treatment. The mat section has also been enlarged and includes illustrations of patient treatment.
The Kremlin's Candidate
Russian counterintelligence chief Colonel Dominika Egorova has been an asset of the CIA for over seven years. She has also been in a forbidden and tumultuous love affair with her handler Nate Nash, mortally dangerous for them both, but irresistible. In Washington, a newly installed administration is selecting its cabinet members. Dominika hears whispers of a Russian operation to place a mole in a high intelligence position. If the candidate is confirmed, the Kremlin will have access to the identities of CIA assets in Moscow, including Dominika. Dominika recklessly immerses herself in the palace intrigues of the Kremlin, searching for the mole's identity and stealing secrets before her time runs out.
The New York Times Biographical Service
A compilation of current biographical information of general interest.
Who's Who of American Women, 1997-1998
WHO'S WHO OF AMERICAN WOMEN is the one essential reference to depend on for accurate & detailed facts on American women of achievement. This new edition includes in-depth biographical profiles of prominent, accomplished women.
Shortchangers
A spoof on the politically correct, featuring a university in the Midwest. So that no one offends anyone, students wear color-coded necklaces, giving their class, ethnic, religious, political and sexual orientation. But as the dean learns some still feel left out, for example, the "vertically challenged," as small people call themselves.
Tertiary Lymphoid Structures
This volume explores the various methods used to study tertiary lymphoid structures (TLS) in pathological situations. Pre-clinical models are also discussed in detail to show how TLS structure, development, and maintenance can be targeted and studied in vivo. The chapters in this book cover topics such as humans and mice; strategies to quantify TLS in order to use it in stained tissue sections; classifying a gene signature form fixed and paraffin-embedded tissues; and development of murine inflammatory models to help look at TLS in the context of infection or malignancy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Tertiary Lymphoid Structures: Methods and Protocols is a valuable resource that increases the reader’s knowledge on immune functions and how they will pave the way to future therapeutic applications.
