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This book focuses on recent progress in mechanobiology from the materials science perspective, encompassing innovative material designs for force measurements and actuation to resolve dynamic mechanobiology and mechanoarchitectonics, by better mimicking physiologically relevant and time-evolving cellular mechanical environments. It also shows the marriage between cutting-edge materials science which enable spatiotemporal manipulation of material and cell dynamics in multi-dimensions and molecular biological techniques such as genome editing and next generation sequencing for cell fate/motility engineering and disease modelling, with the aim of providing valuable insights into the latest technological advances and discoveries in areas such as stem cell, fibroblast, heart, tumour, and epithelial mechanobiology.
Experts describe state-of-the-art micro-nano techniques for cell mechanobiology and introduce the most recent advances in the field.
This book provides comprehensive coverage of smart biomaterials and their potential applications, a field that is developing at a very rapid pace. Because smart biomaterials are an emerging class of biomaterials that respond to small changes in external stimuli with large discontinuous changes in their physical properties, they have been designed to act as an “on–off” switch for, among others, bio separation, immunoanalysis, drug delivery technologies, gene therapy, diagnostics, bio sensors and artificial muscles. After an introduction to the topic and the history of smart biomaterials, the author gives the reader an in-depth look at the properties, mechanics, and characterization of smart biomaterials including hydrogels, particles, assemblies, surfaces, fibers and conjugates. Information on the wide range of applications for these materials follows, including drug delivery, tissue engineering, diagnostics, biosensors, bio separation and actuators. In addition, recent advances in shape memory biomaterials as active components of medical devices are also presented.
The electrospinning method has the unique ability to produce structured polymeric fibers on the micro or nano scale and to generate novel materials for food and healthcare purposes. The potential of electrospun nanofibers for human healthcare applications is promising, for example, in tissue/organ repair and regeneration, in medical diagnostics and instrumentation, and as vectors to deliver drugs and therapeutics, as biocompatible and biodegradable medical implant devices, as protective fabrics against environmental and infectious agents in hospitals and general surroundings. Furthermore, considerable effort has been directed toward developing scaffolds using biodegradable and biocompatible ...
Surface engineering provides one of the most important means of engineering product differentiation in terms of quality, performance, and lifecycle cost. It is essential to achieve predetermined functional properties of materials such as mechanical strength, biocompatibility, corrosion resistance, wear resistance, and heat and oxidation resistance. Surface Engineering of Biomaterials addresses this topic across a diverse range of process technologies and healthcare applications. Introduces biomaterial surface science and surface engineering and includes criteria for biomaterial surface selection Focuses on a broad array of materials including metals, ceramics, polymers, alloys, and composites Discusses corrosion, degradation, and material release issues in implant materials Covers various processing routes to develop biomaterial surfaces, including for smart and energy applications Details techniques for post-modification of biomaterial surfaces This reference work helps researchers working at the intersection of materials science and biotechnology to engineer functional biomaterials for a variety of applications.
A unique overview of the manufacture of and applications for materials nanoarchitectonics, placing otherwise hard-to-find information in context. Edited by highly respected researchers from the most renowned materials science institute in Japan, the first part of this volume focuses on the fabrication and characterization of zero to three-dimensional nanomaterials, while the second part presents already existing as well as emerging applications in physics, chemistry, biology, and biomedicine.
Additive manufacturing, also called rapid prototyping or 3D printing is a disruptive manufacturing technique with a significant impact in electronics. With 3D printing, bulk objects with circuitry are embedded in the volume of an element or conformally coated on the surface of existing parts, allowing design and manufacturing of smaller and lighter products with fast customisation. The book covers both materials selection and techniques. The scope also covers the research areas of additive manufacturing of passive and active components, sensors, energy storage, bioelectronics and more.
Shape Memory Polymer Composites discusses the fabrication of smart polymer composites with their material characterization. It covers shape memory polymer composites with two different types of reinforcement: shape memory polymer nanocomposites and shape memory hybrid composites. Enhancing the mechanical and thermomechanical properties of the shape memory polymers makes them an important class of materials for new age applications ranging from aerospace, biomedical, electronics, to marine engineering. The book discusses how shape memory polymer composites exhibit remarkable mechanical properties, as compared to its corresponding shape memory polymers, without compromising the shape memory behavior. It presents experimental case studies of polymers, polymer composites, and multiphase composites, explaining the effects of each reinforcement on the material properties with corresponding simulation. The book will be a useful reference for industry professionals and researchers involved with the mechanics of shape memory materials.