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Ziel dieser Arbeit soll es sein, die kritischen und technischen Aspekte des Cloud Computings, insbesondere die rechtlichen und sicherheitsrelevanten Eckpunkte der nicht lokalen elektronischen Datenverarbeitung, dem Leser näher zubringen. Einige dieser Aspekte sind bereits der Öffentlichkeit zugänglich, werden jedoch von der breiten Masse der Nutzer und Entwickler nicht wahrgenommen. Dieser Mangel zieht sich durch alle Bereiche des Cloud Computings hindurch. Beginnend bei den eingesetzten Basistechnologien und den allgemeinen technischen Spezifikationen, bis hin zu allgemeinen Fragen der Sicherheit jeder einzelnen Technologie. Auch Infrastrukturelle Fragen, wie beispielsweise die Verfügba...
This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug discovery pathway. The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and validation area. The lead generation part as a next step focuses on the requirements and technologies to identify new small molecules as lead compounds for further optimization; in a second section the technologies to identify biologics as leads are addressed. The final part focuses on the pharmacological models and technologies to characterize new compounds and the impact of biomarkers to facilitate the transfer of drug candidates into the development phase.
This book challenges earlier understandings of early modern dissertations as unimaginative academic exercises. It argues for their continuous importance in scholarly and scientific discourse, and describes the richness and diversity of their subjects and themes. The book contains a complete catalogue of the almost 20,000 Swedish dissertations defended in Uppsala, Lund and Åbo, 1600 to 1820. The catalogue includes longer comments and descriptions of a few thousand of these dissertations, and also gives an analysis of how different subjects have evolved over time.