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Henry Kaplan and the Story of Hodgkin's Disease
A “compelling—and wonderfully told” biography of the American physician who pioneered a treatment for a cancer of lymph tissue (Wall Street Journal). In the 1950s, ninety-five percent of patients with Hodgkin’s disease, a cancer of lymph tissue which afflicts young adults, died. Today most are cured, due mainly to the efforts of Dr. Henry Kaplan. Henry Kaplan and the Story of Hodgkin’s Disease explores the life of this multifaceted, internationally known radiation oncologist, called a “saint” by some, a “malignant son of a bitch” by others. Kaplan’s passion to cure cancer dominated his life and helped him weather the controversy that marked each of his innovations, but it...
TOP Bulletin
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Use of the Normalized Difference Vegetation Index (NDVI) to Assess Land Degradation at Multiple Scales
This report examines the scientific basis for the use of remotely sensed data, particularly Normalized Difference Vegetation Index (NDVI), primarily for the assessment of land degradation at different scales and for a range of applications, including resilience of agro-ecosystems. Evidence is drawn from a wide range of investigations, primarily from the scientific peer-reviewed literature but also non-journal sources. The literature review has been corroborated by interviews with leading specialists in the field. The report reviews the use of NDVI for a range of themes related to land degradation, including land cover change, drought monitoring and early warning systems, desertification proc...
The Architecture of Evolution
In the final decades of the twentieth century, the advent of evolutionary developmental biology (evo-devo) offered a revolutionary new perspective that transformed the classical neo-Darwinian, gene-centered study of evolution. In The Architecture of Evolution, Marco Tamborini demonstrates how this radical innovation was made possible by the largely forgotten study of morphology. Despite the key role morphology played in the development of evolutionary biology since the 1940s, the architecture of organisms was excluded from the Modern Evolutionary Synthesis. And yet, from the beginning of the twentieth century to the 1970s and ’80s, morphologists sought to understand how organisms were buil...
Human Hybridomas and Monoclonal Antibodies
Soon after Kohler and Milstein described the use of somatic cell hybridization for the production of murine monoclonal antibodies of desired specificity, this relatively simple technique became widely applied. Indeed, production of murine monoclonal antibodies is now considered routine by immunologists and nonimmunologists alike. However, as heterologous proteins, mouse monoclonal antibodies have one major limitation: they are immunogenic in man and, hence, their use in vivo is severely limited. An obvious solution to this problem is to produce human hybridomas with the same techniques used for the production of rodent hybrids. Unfortunately, the history of human hybridomas has been marked b...
International Seminar on Nuclear War and Planetary Emergencies
This was the first of a number of seminars dealing with one of the most complex of the new challenges in the 21st century, which call for the participation of a broad range of experts. Eminent economists, decision-makers, defence specialists, political analysts and sociologists presented their views and participated in the debates. In the wake of the dramatic event of 11 September 2001, the Afghanistan war and the resurgence of terrorist acts on all the continents, a host of issues were reconsidered and the role of science and technology was reassessed. The 27th Session was primarily oriented toward the definition of the new types of confrontation, and the identification of various factors and issues that gave rise to them and global trends.The proceedings have been selected for coverage in: ? Index to Scientific & Technical Proceedings (ISTP CDROM version / ISI Proceedings)? Index to Social Sciences & Humanities Proceedings? (ISSHP? / ISI Proceedings)? Index to Social Sciences & Humanities Proceedings (ISSHP CDROM version / ISI Proceedings)
Annals of the History and Philosophy of Biology 11/2006
The name DGGTB (Deutsche Gesellschaft für Geschichte und Theorie der Biologie; German Society for the History and Theory of Biology) refl ects recent history as well as German tradition. The Society is a relatively late addition to a series of German societies of science and medicine that began with the »Deutsche Gesellschaft für Geschichte der Medizin und der Naturwissenschaften«, founded in 1910 by Leipzig University's Karl Sudhoff (1853-1938), who wrote: »We want to establish a ,German' society in order to gather German-speaking historians together in our special disciplines so that they form the core of an international society«. Yet Sudhoff, at this time of burgeoning academic int...
Framing in Sustainability Science
This open access book offers both conceptual and empirical descriptions of how to “frame” sustainability challenges. It defines “framing” in the context of sustainability science as the process of identifying subjects, setting boundaries, and defining problems. The chapters are grouped into two sections: a conceptual section and a case section. The conceptual section introduces readers to theories and concepts that can be used to achieve multiple understandings of sustainability; in turn, the case section highlights different ways of comprehending sustainability for researchers, practitioners, and other stakeholders. The book offers diverse illustrations of what sustainability concep...
Regenerative Agriculture
The food system is our last coal-fired power station, our last diesel engine. This book is a trans-disciplinary approach to what needs to be done to make our food system sustainable and to regenerate soil and water resources, habitat, economy and society. The book brings back classical principles of agronomy and integrates economic, agro-ecological and social perspectives, drawing on a wealth of expertise on the political economy of the food system, Conservation Agriculture, and long-term field experiments. Regenerative agriculture builds on known knowns – like crop rotation, water and nutrient requirements, soil and water conservation, farm-gate prices, international trade and supply chai...
