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Disentangling the Relationship of Subjective Cognitive Decline and Depressive Symptoms in the Development of Cognitive Decline and Dementia
Abstract: Introduction Subjective cognitive decline (SCD) and depressive symptoms (DS) frequently co-occur prior to dementia. However, the temporal sequence of their emergence and their combined prognostic value for cognitive decline and dementia is unclear. Methods Temporal relationships of SCD, DS and memory decline were examined by latent difference score modeling in a high-aged, population-based cohort (N = 3217) and validated using Cox-regression of dementia-conversion. In 334 cognitively unimpaired SCD-patients from memory-clinics, we examined the association of DS with cognitive decline and with cerebrospinal fluid (CSF) Alzheimer's disease (AD) biomarkers. Results In the population-b...
Obesity Epidemiology
During the past twenty years there has been a dramatic increase in obesity in the United States. An estimated thirty percent of adults in the US are obese; in 1980, only fifteen percent were. The issue is gaining greater attention with the CDC and with the public health world in general. This book will offer practical information about the methodology of epidemiologic studies of obesity, suitable for graduate students and researchers in epidemiology, and public health practitioners with an interest in the issue. The book will be structured in four main sections, with the majority of chapters authored by Dr. Hu, and some authored by specialists in specific areas. The first section will consid...
Social Isolation in Modern Society
Social isolation has serious repercussions for people and communities across the globe, yet knowledge about this phenomenon has remained rather limited – until now. The first multidisciplinary study to explore this issue, Social Isolation in Modern Society integrates relevant research traditions in the social sciences and brings together sociological theories of social networks and psychological theories of feelings of loneliness. Both traditions are embedded in research, with the results of a large-scale international study being used to describe the extent, nature and divergent manifestations of social isolation. With a new approach to social inequality, this empirically based study includes concrete policy recommendations, and presents a clear insight into personal, social and socio-economic causes and the consequences of social isolation.
Annuario pontificio
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The Frontline
Saturday night outside the tube: God, strip bars, weed, crack, lost old men, unemployed actors and vegans all collide in a riptide of chaos on the streets of London. There's Beth the reformed Christian and Erkenwald the hot-dog seller, old Ragdale on a quest to find his daughter, actor-playwright and egomaniac Mordechai Thurrock, and Cockburn, Elliot and Clayton the dealers and junkies whose trade both sustains and destroys the lives of those around them. In this vibrant and darkly comic new play, a dozen private stories emerge and their voices give utterance to a storm of subjects and feelings: pop culture and sexual fantasy, the ruins of empire and the delusions of religion, foreign oil and prehistoric London. A panorama of contemporary London encompassing the cruel and the tender, the gutter and the stars. Che Walker's The Frontline premiered at Shakespeare's Globe Theatre, London, in July 2008. 'The brusque, bathetic poetry of back-street Camden is Walker's lingua franca. Flesh and blood and honour are his themes' Time Out on Ché Walker's Flesh Wound
Multiple Pathways of Cognitive Aging
"The empirical study of aging and cognition has progressed tremendously over the past 50-plus years. Much of the original research had its roots in the medical realm as investigators sought to characterize cognitive deficits associated with aging. For the most part, this research adhered to a biomedical model, in which aging was considered akin to a disease, and the focus was on understanding patterns of decline that were assumed to be an inevitable part of getting older (Hess & Blanchard-Fields, 1996). Indeed, aging was often studied by comparing patterns of decline to those associated with atypical populations with specific diseases or cortical lesions/insults (e.g., West, 1996). The study...
Dialectic and Its Place in the Development of Medieval Logic
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