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Learning in 21st Century Schools
In 2010 the Education Network organized an event that examined the state of school infrastructure in the region and the financial role of the private sector. Infrastructure and Learning in the Twenty-First Century was held in Santiago, Chile, on October 26 and 27, 2010. This book contains the presentations made at the conference, edited and, in some cases, revised for publication. The chapters of the book follow the conference agenda, which focused on designing, financing, building, and maintaining school buildings.
Characteristic clinical immune phenotypes and molecular mechanisms associated with inflammatory diseases
The systemic inflammatory response is evident in inflammatory diseases, and the immune system secretes many cytokines involved, resulting in a robust immune response. For example, the pathogenesis of sepsis includes abnormal immune cell activation in the early stages as well as sepsis-related immunosuppression. During the immunosuppressive phase, CD4+ T cells, CD8+ T cells, Th17 cells, and γδ T cells are reduced while regulatory T cells increase. At the same time, T lymphocytes and neutrophils, as immune effector cells, interact with each other and play a key role in regulating the immune response to immune-inflammatory diseases. The increased release of neutrophil extracellular trap networks (NETs) by neutrophils leads to a significant upregulation of NETs-DNA-MPO, which further aggravates the septic inflammatory response and organ functional impairment. Therefore, it is important to deeply investigate the characteristic clinical immune phenotypes and molecular mechanisms associated with inflammatory diseases, and targeting therapies against them may provide new ideas for the precise treatment of diseases.
Agenda
AGENDA occupies the territory between a monograph, diary, and a collection of essays, interviews, and conversations, produced by JDS Architects with a wide range of contributors and collaborators. Starting from the belief that an agenda is not simply an expression of individual intentions, but rather a vector for the production of new realities, AGENDA addresses the need for architecture to transform itself in an era of ecological and economic crisis. Change, the buzzword of the last U.S. presidential campaign, is indeed the order of the day, and AGENDA explores exactly what kind of change will be needed if architects are to assume a political and social agency in this new landscape. The book seeks to define not only the work of JDS Architects, but also the challenges and situations confronting young architectural practices emerging at a time of crisis. An ambitious attempt to describe the conditions within which architecture is produced today.
建築と都市
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Aprendizaje en las escuelas del siglo XXI
En 2010, la Red de Educación organizó un seminario que examinó el estado de la infraestructura escolar en América Latina y el Caribe y el papel financiero del sector privado. El seminario de Infraestructura y Aprendizaje en el Siglo XXI se realizó en Santiago, Chile entre el 26 y 27 de octubre de 2010. Este libro recopila las presentaciones realizadas durante la conferencia, editados y, en algunos casos, revisados parea su publicación. Los capítulos de este libro siguen el orden de la agenda de la conferencia, enfocándose en el diseño, financiamiento, construcción y mantenimiento de edificios escolares.
La autoconciencia del cosmos
Segundo volumen de la serie Casi Tischreden, La autoconciencia del cosmos se centra en los temas abordados en El sentido religioso, primer volumen del Curso básico de cristianismo en el que Luigi Giussani recoge su itinerario de pensamiento y de experiencia. Para el autor, el sentido religioso pertenece a la experiencia elemental de todo hombre, es decir, a ese nivel de la conciencia en el que el yo se pregunta por el significado de la vida, de la realidad y de todo lo que sucede. Por ello, éstas son las palabras que más se repiten en los diálogos que presentamos aquí. Los capítulos están organizados atendiendo a los argumentos que constituyen el fondo de cada uno de los diálogos: el ímpetu original del corazón, la dinámica del conocimiento, la dinámica de la libertad, el valor del signo en la experiencia humana.
Green life
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