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The DNA Damage Response: Implications on Cancer Formation and Treatment
The ?eld of cellular responses to DNA damage has attained widespread recognition and interest in recent years commensurate with its fundamental role in the ma- tenance of genomic stability. These responses, which are essential to preventing cellular death or malignant transformation, are organized into a sophisticated s- tem designated the “DNA damage response”. This system operates in all living organisms to maintain genomic stability in the face of constant attacks on the DNA from a variety of endogenous by-products of normal metabolism, as well as exogenous agents such as radiation and toxic chemicals in the environment. The response repairs DNA damage via an intricate cellular signal...
Nineteenth-Century Salesian Pentecost, The
In the wake of the French Revolution and other upheavals, Don Bosco (1815–1888) and other nineteenth-century founders and spiritual leaders contributed to the development of spiritual practices and perspectives on the Christian life that have been described as the “Salesian Pentecost.” Here are translations of and commentaries on the little-known spiritual writings of Don Bosco, his collaborators, and his contemporaries involved in the Salesian Pentecost. These diverse persons, fully engaged in apostolic ministry or occupied with the demands of ordinary life as lay women and men, were at the same time engaged in conscious spiritual practices that sought the interior exchange of the heart of Jesus for the human heart.
International Review of Cytology
International Review of Cytology presents current advances and comprehensive reviews in cell biology—both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Authored by some of the foremost scientists in the field Provides up-to-date information and directions for future research Valuable reference material for advanced undergraduates, graduate students and professional scientists
