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Het Marketingfacts Jaarboek is het meest actuele handboek over de staat van online marketing in Nederland anno nu. Het boek helpt je als marketeer nog beter te bepalen welke middelen je inzet en met welke doelstellingen. Het is als de onlinemarketingbijbel onmisbaar bij het maken en schrijven van nieuwe marketingplannen. Het boek hoort thuis op de hoek van het bureau van iedere ervaren marketing- en communicatiespecialist. Ook wordt het boek door veel hogescholen en universiteiten ingezet als studieboek voor marketing- en communicatieopleidingen. Dit jaar publiceren we het Marketingfacts Jaarboek voor alweer de 10e keer. Wat in het eerste jaar begon als een dunne handige gids over het verand...
Avviare un’attività di commercio elettronico che generi profitto non è così semplice come si possa credere: la Rete oggi è ipercompetitiva; per differenziarsi dalla concorrenza servono idee innovative, competenze specifiche, partner affidabili, strategie concrete e budget sostenibili. Ecco allora la necessità di una guida pratica e completa per chi vuole creare e gestire un e-commerce vincente. I sette capitoli di cui si compone il volume illustrano tutte le potenzialità del commercio elettronico, svelano i segreti del mestiere e raccontano con puntualità i dettagli che hanno permesso alle aziende dell’era dotcom - come Amazon - di fare la differenza. In un percorso progressivo ma non vincolante, il lettore è guidato dalla fase embrionale dell’idea alla gestione operativa e concreta di un’azienda di e-commerce, passando dalla compilazione del business plan alla pianificazione delle strategie di web marketing insieme alla scelta del brand, del dominio, del logo, della piattaforma, del servizio di hosting e via dicendo.
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The last two decades have seen a huge expansion in research in the area of lysosomal storage disorders, which has substantially extended our understanding of both the scientific and the clinical basis of these diseases. Lysosomal Storage Disorders: A Practical Guide is the fruit of an ambitious project aiming to review both the scientific and the clinical aspects of lysosomal storage disorders, resulting in this accessible volume, which gives an up-to-date overview of the subject. There is substantial scientific interest in these diseases: new advances in small molecule therapy are likely to be useful in the near future, and trials are already underway. Lysosomal storage disorders offer a un...
JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
There is a dynamism among current ideas on AD/HD research which is extraordinarily encouraging as we look to the future and the resolution of the problems of AD/HD. We can have more confidence than of late that we can determine and rate the problems grouped under the rubric of AD/HD (chapter 1), delineate them with respect to some prominent (if not all) related behavioural disruptions (chapter 2) and have some confidence in an inter-cultural commonality of a problem that may respond to attention from professional care-givers (chapter 4). We are standing already at the second stage of an understanding and attribution of genetic and environmentally mediated traits (chapter 3, 9 and 10): that t...
Fabry disease is an X-linked inborn error of metabolism wherein deficiency of a lysosomal enzyme results in systemic deposition of glycosphingolipids. Storage deposition, and hence pathological disease, occurs preferentially in renal glomerular and tubular epithelial cells, myocardial cells, heart valve fibrocytes, neurons of dorsal root ganglia, and in endothelial smooth muscle cells of blood vessels. Thus, Fabry disease is a multi-system disorder, albeit with considerable phenotypic heterogeneity in onset and in severity; however, it is progressive, exhibits extensive morbidity, and is life-threatening. Within the past two decades, there has been a radical change in the natural course Fabr...