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Systemic Inflammation in Severe Infectious Diseases
Hospital-acquired infections are common and often result in life-threatening complications, mostly facing critically ill patients in the intensive care unit. Patients with hospital-acquired infections may die from bacteremia/fungal/viral infection or hyperinflammatory complications because of an uncontrolled over-activation of the innate immune system with pathological levels of circulating proinflammatory cytokines, or from multiorgan failure. In addition to eliciting a robust inflammatory response, it paradoxically renders the host in an immunocompromised state at the late stage of the disease progression. Severe infectious diseases, including sepsis and septic shock are among the most common reasons for death in hospitals. Sepsis is an infection-induced syndrome characterized by a generalized inflammatory state and represents a frequent complication in surgical patients and in immunocompromised patients. Sepsis is a common, expensive, and frequently associated with a fatal outcome. Every 3 to 4 seconds somebody dies with sepsis, and it is one of the leading causes of death worldwide.
Measurement in Machining and Tribology
This book presents the research advances in the science of measurement, giving special focus to the field of machining and tribology. Topics such as dimensional metrology, precision measurements, industrial metrology, accuracy and precision in measurement are covered. Also theoretical aspects such as modelling and simulation are highlighted.
Sepsis - Pro-Inflammatory and Anti-Inflammatory Responses
Sepsis is a serious condition that is associated with high mortality despite advanced modern medical treatment. Recent years have witnessed novel paradigms describing host responses in sepsis. In particular, the delicate balance between pro- and anti-inflammatory reactions has been subject to intense research. This volume in the book series 'Contributions to Microbiology' presents the state of the art in this rapidly expanding field of research. Leading international experts have contributed with reviews on the most relevant topics in the field such as clinical aspects, pathways of sepsis and pro- and anti-inflammatory mechanisms as well as their regulation. The book will be a valuable source of up-to-date information for clinicians, microbiologists, immunologists, and students with an interest in the complex regulation of host responses during microbial sepsis.
Digitizing Production Systems
This book contains selected papers from International Symposium for Production Research 2021, held on October 7–9, 2021, online, Turkey. The book reports recent advances in production engineering and operations. It explores topics including production research; production management; operations management; industry 4.0; industrial engineering; mechanical engineering; engineering management; and operational research. Presenting real-life applications, case studies, and mathematical models, this book is of interest to researchers, academics, and practitioners in the field of production and operation engineering. It provides both the results of recent research and practical solutions to real-world problems.
Machine Tools
Successful producers of machine tools today must offer customers highly efficient and accurate machines. This can only be achieved with the help of modern software in research, construction, production and quality control. Trends in development are oriented towards modular construction machines. The application of modern tools and the progressive construction of headstock has increased cutting speeds, thus significantly increasing the machine's productivity. The first section of the book is focused on trends in the development of machines. A second very significant machine parameter is accuracy. The rigidity of the machine is a necessary condition for achieving its required accuracy. The second part of the book is dedicated to the effect of the individual constructional nodes on stability, the optimization of system rigidity, and the measuring of the accuracy of the machining tools. The aim of the third and final section of the book is to point out the widest possibilities for the application of machine tools in industry. An example is presented of the application of machining tools in the orthoses manufacture.
Proceedings of the International Symposium for Production Research 2019
This book discusses the conference that forms a unique platform to bring together academicians and practitioners from industrial engineering and management engineering as well as from other disciplines working on production function applying the tools of operational research and production/operational management. Topics treated include: computer-aided manufacturing, Industry 4.0, big data and analytics, flexible manufacturing systems, fuzzy logic, industrial applications, information technologies in production management, optimization, production economy, production planning and control, productivity and performance management, project management, quality management, risk analysis and management, and supply chain management
Mechatronics 2017
This book presents nearly 90 carefully selected contributions at the 12th International Conference Mechatronics, which took place in Brno, Czech Republic on 6–8 September 2017. Reflecting the most progressive and constantly changing areas of mechatronics, these proceedings includes papers concerning modeling and simulation, automatic control, robotics, sensors and actuators, electrical machines, and energy harvesting. It not only offers inspiration, but also deepens readers’ interdisciplinary and integrated understanding of modern engineering. The book is intended for experts in the integration of electronic, mechanical, control and computer sciences.
Research and Advanced Technology for Digital Libraries
This book constitutes the refereed proceedings of the International Conference on Theory and Practice of Digital Libraries, TPDL 2013 (formerly European Conference on Research and Advanced Technology for Digital Libraries, ECDL) held in Valletta, Malta, in September 2013. The 24 full papers, 13 short papers, 22 posters and 8 demonstrations presented in this volume were carefully reviewed and selected from 158 submissions. The papers cover a wide range of research topics, clustered in four broader areas: foundation, infrastructures, content, and services. They have been organized in topical sections on conceptual models and formal issues, aggregation and archiving, user behavior, digital curation, mining and extraction, architectures and interoperability, interfaces to digital libraries, semantic web, information retrieval and browsing, and preservation. Also included are 6 tutorials and 2 panels.
