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Parkinson's Disease: Insights from Drosophila Model
Parkinson's disease (PD) is a medical condition that has been known since ancient times. It is the second most common neurodegenerative disorder affecting approximately 1% of the population over 50 years. It is characterized by both motor and non-motor symptoms. Most of PD cases are sporadic while 5-10% cases are familial. Environment factors such as exposure to pesticides, herbicides and other heavy metals are expected to be the main cause of sporadic form of the disease. Mutation of the susceptible genes such as SNCA, PINK1, PARKIN, DJ1, and others are considered to be the main cause of the familial form of disease. Drosophila offers many advantages for studying human neurodegenerative dis...
Dopamine
The chemical basis of human emotions has been an exciting aspect in biology. The "feel-good chemical" dopamine (DA) is a hormone and also a neurotransmitter, which performs a critical role in reward and movement control in the brain. DA also performs multiple other functions outside the brain. Regulating unrelated critical biological functions makes this chemical a vital factor for sustaining life in both health and disease. Dopamine - Health and Disease is an endeavour with an objective to understand and appreciate the biological functions of DA in human wellbeing and its potential utility in biomedical research. This effort will supplement scientific and non-scientific communities in stimulating a critical understanding of the biological purpose of "ticklish" DA, which eventually supports the human relentless effort to reduce the burden of disease. As the most exciting molecule,dopamine directly impacts day-to-day life. Anyone who has an eye for health and disease-related concepts will find this book a good read.
Drosophila melanogaster
This book contains 12 chapters divided into two sections. Section 1 is "Drosophila - Model for Genetics." It covers introduction, chromosomal polymorphism, polytene chromosomes, chromosomal inversion, chromosomal evolution, cell cycle regulators in meiosis and nongenetic transgenerational inheritance in Drosophila. It also includes ecological genetics, wild-type strains, morphometric analysis, cytostatics, frequencies of early and late embryonic lethals (EEL and LEL) and mosaic imaginal discs of Drosophila for genetic analysis in biomedical research. Section 2 is "Drosophila - Model for Therapeutics." It explains Drosophila as model for human diseases, neurodegeneration, heart-kidney metabol...
Bioprospecting of Indigenous Bioresources of North-East India
This work is a comprehensive information on the indigenous bioresources of North Eastern India with the scope of bioprospecting for discovery and commercialization of new sources and products and long-term ecological balance. The exploration, conservation and sustainable utilization of bioresources of world’s Megabiodiversity Hotspots are undeniable. North Eastern India is a recognised biodiversity hot spot where the evolutionary forces are at its optimum, making this region as centre of origin for many species. Although little bit exploratory studies have been conducted in this part of the globe but a scientific exploitation of the bioresources is almost lacking. Unscientific exploitation...
The Shorter Wisden India Almanack 2013
The Shorter Wisden is a compelling distillation of what's best in its bigger brother. Wisden India's digital version includes the influential Notes by the Editor, all the front-of-book articles, reviews, obituaries and all aspects of Indian cricket including Test Matches and the Indian Premier League. Contributors include Bishan Singh Bedi, Anil Kumble, Mahela Jayawardhene, Sanjay Manjrekar, Shashi Tharoor, Gideon Haigh, Kamila Shamsie and many more...
Democracy's XI
Bestselling author and journalist Rajdeep Sardesai narrates the story of post-Independence cricket through the lives of 11 extraordinary Indian cricketers who portray different dimensions of this change; from Dilip Sardesai and Tiger Pataudi in the 1950s to Mahendra Singh Dhoni and Virat Kohli today
Physics and Contemporary Needs
This volume consists of lectures delivered at the Sixth Inter national Nathiagali Summer College on Physics and Contemporary Needs held at Islamabad from June 15 to July 2, 1981. The College used to be held at one of the scenic hill resorts of Pakistan, Nathiagali, hence the name of the College. The College was organized by the Pakistan Atomic Energy Commission (PAEC), under the patronage of the International Centre for Theoretical Physics (ICTP), Trieste, with a view to providing an opportunity for local physicists and physicists from developing countries for learning of the latest developments in various branches of physics. The University Grants Commission provided a financial grant for t...
