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Post-transcriptional Control of Gene Expression
Many important cellular processes rely on posttranscriptional control of gene expression. This book describes the mechanisms of gene expression at this level that occur in the cytoplasm of prokaryotes and eukaryotes. Several introductory chapters discuss the general principles of translation and mRNA stability. The interactions of mature mRNA with the translational machinery, the components of mRNA degradation and antisense RNA are surveyed. Subsequent chapters discuss protein folding, transport, modification and degradation. The book is an invaluable source of information for both newcomers and those wishing an overview of the field.
Dynamic System Modelling and Analysis with MATLAB and Python
Dynamic System Modeling & Analysis with MATLAB & Python A robust introduction to the advanced programming techniques and skills needed for control engineering In Dynamic System Modeling & Analysis with MATLAB & Python: For Control Engineers, accomplished control engineer Dr. Jongrae Kim delivers an insightful and concise introduction to the advanced programming skills required by control engineers. The book discusses dynamic systems used by satellites, aircraft, autonomous robots, and biomolecular networks. Throughout the text, MATLAB and Python are used to consider various dynamic modeling theories and examples. The author covers a range of control topics, including attitude dynamics, attit...
Stochastic Regulation of the Interleukin-4 Gene
This book focuses on the expression variability of highly regulated genes in multi-cellular organisms through a multidisciplinary approach combining quantitative measurements and mathematical modeling. For this purpose, the cytokine gene Interleukin-4 (IL-4) in murine type-2 (Th2) lymphocytes was chosen as prototypical model system of an inducible gene regulated at the epigenetic and transductional level. As many cytokines, IL-4 is expressed in a probabilistic manner, but the underlying molecular mechanisms behind this phenomenon are still unresolved. Through an iterative process of quantitative measurements and mathematical analysis, the author develops a computational model able to predict...
Green Fluorescent Protein
One of the most important recent discoveries in science is the green fluorescent protein, isolated from a bioluminescent jellyfish. The gene that codes for this protein is active in any type of cell, from microbes to humans, producing a "day-glo" dye visible as a bright green light in the microscope. The power of the gene is that by using recombinant DNA technology. GFP can be spliced to any protein, essentially painting that protein green. When such a spliced protein is inside a cell. Further, time-lapse microscopy can be used to examine how that protein and the cellular components that it is part of move within the cell during the cell's life cycle. This Methods in Enzymology volume deals ...
The New York Times Biographical Service
A compilation of current biographical information of general interest.
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