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Everyone of us is who and where we are today because of the efforts and decisions of those who came before us -- our ancestors. This book traces the history of nine of my ancestral families, from their small farming villages in Germany, through the wrenching decision to leave cherished roots in Europe, to the planting of new roots in southern Indiana. The book is intended primarily for members of my family, but others may find some interest in a small microcosm of the American experience.
The Peace of Utrecht (1713) was perhaps the first political treaty that had a global impact. It not only ended a European-wide conflict, but also led to a cessation of hostilities on the American continent and Indian subcontinent, as well as naval warfare worldwide. More than this, however - as the chapters in this volume clearly demonstrate - the treaty marked an important step in the development of an integrated world-wide political system. By reconsidering the preconditions, negotiations and consequences of the Peace of Utrecht - rather than focusing on previous concerns with international relations and diplomacy - the contributions to this collection help embed events in a richer context...
Rational pharmacotherapy of the inner ear will become an important issue in treatment of inner ear diseases today and in the future. The contributions of some of the experts in the field are gathered in the present volume dedicated to all aspects of the pharmacology and the possible local and systemic treatment of inner ear diseases. Major topics include new aspects of human inner ear anatomy, neurotransmission, ion channels, vascular system, immunology, excitotoxicity, modulation of cell cycle, regeneration and differentiation, as well as new aspects of basic mechanisms at the cellular and molecular levels. A major feature of this volume is that it brings together both basic researchers and physicians to evaluate new experimental therapies and discuss future clinical strategies in the treatment of cochleo-vestibular disorders. Therefore, it will prove interesting to both scientists and clinicians in sensory physiology and auditory systems.
Las técnicas de cultivos celulares de células animales se han convertido en herramientas fundamentales de la investigación básica y aplicada de la Biomedicina. El conocimiento actual del ciclo celular, la mitosis y la meiosis, la estructura de los cromosomas, la clonación, la fisiología de la membrana y la interacción celular, numerosos aspectos sobre el cáncer y su diagnóstico, el envejecimiento a nivel celular, etc. no hubieran sido posibles sin la investigación en cultivo de células animales y humanas. De sus aplicaciones han derivado también desarrollos industriales y técnicas de apoyo al diagnóstico clínico y a la terapéutica. El libro comienza con un análisis históric...
The main function of the sensory systems is the transducing of external stimuli into bioelectrical signals, which are conducted through afferent pathways from sensory epithelia to the brain. However, it is known that descending projections are ubiquitous in the different sensory modalities, and in the case of auditory efferents connect the cerebral cortex with sensory receptor cells. Several functions have been attributed to the efferent system, including protection to acoustic trauma, unmasking of auditory stimuli in background noise, balance of interaural sensitivity and some cognitive functions like modulation of cochlear sensitivity during selective attention to auditory or visual stimul...
Recursos humanos en investigación y desarrollo.--V.2.
First multi-year cumulation covers six years: 1965-70.