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Creating the Identity of Alienation from 'the Unpopular Patient' to Body Modification
  • Language: en
  • Pages: 70
The Deadly Secrets of C. Difficile - Insights into Host-Pathogen Interaction, Volume II
  • Language: en
  • Pages: 161
The Deadly Secrets of C. Difficile - Insights into Host-Pathogen Interaction
  • Language: en
  • Pages: 319
Updates on Clostridioides difficile in Europe
  • Language: en
  • Pages: 368

Updates on Clostridioides difficile in Europe

This fully updated second edition outlines the currently available clinical, epidemiological and experimental data on Clostridioides difficile infections(CDI) with special emphasis on studies and results achieved in Europe. The incidence and severity of CDI has increased significantly over the last decade, and the book explains why C. difficile, recently reclassified as Clostridioides difficile, remains a significant challenge, also from economic perspective, to health care systems all over the world. The different reservoirs of this ubiquitous microorganism are reviewed as well as the different factors contributing to its virulence, such as toxins and biofilm formation. The rapid evolution ...

Uptake and Trafficking of Protein Toxins
  • Language: en
  • Pages: 261

Uptake and Trafficking of Protein Toxins

  • Type: Book
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  • Published: 2017-12-01
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  • Publisher: Springer

This volume focuses on the transport of medically relevant bacterial protein toxins into mammalian cells, and on novel pharmacological strategies to inhibit toxin uptake. The first chapters review our current understanding of the cell-surface receptors and cellular transport processes of Clostridium botulinum neurotoxins, Clostridium botulinum C3 toxin, Clostridium difficile toxins, binary clostridial enterotoxins, anthrax toxins and diphtheria toxin. In brief, specific binding/transport (B) subunits deliver the enzyme (A) subunits into the cytosol, where the latter modify their substrates, producing cytotoxic effects and the characteristic toxin-associated diseases. Key mechanisms for the t...

Updates on Clostridium difficile in Europe
  • Language: en
  • Pages: 262

Updates on Clostridium difficile in Europe

  • Type: Book
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  • Published: 2018-01-29
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  • Publisher: Springer

This book outlines the currently available clinical, epidemiological and experimental data on Clostridium difficile infection (CDI) with special emphasis on studies and results achieved in Europe. The incidence and severity of CDI has increased significantly over the last decade, and the book explains why C. difficile, recently reclassified as Clostridioides difficile, remains a significant challenge, also from economic perspective, to health care systems all over the world. The different reservoirs of this ubiquitous microorganism are reviewed as well as the different factors contributing to its virulence, such as toxins and biofilm formation. The rapid evolution of antibiotic resistance is...

Health Informatics Vision: From Data via Information to Knowledge
  • Language: en
  • Pages: 422

Health Informatics Vision: From Data via Information to Knowledge

  • Type: Book
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  • Published: 2019-08-06
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  • Publisher: IOS Press

The latest developments in data, informatics and technology continue to enable health professionals and informaticians to improve healthcare for the benefit of patients everywhere. This book presents full papers from ICIMTH 2019, the 17th International Conference on Informatics, Management and Technology in Healthcare, held in Athens, Greece from 5 to 7 July 2019. Of the 150 submissions received, 95 were selected for presentation at the conference following review and are included here. The conference focused on increasing and improving knowledge of healthcare applications spanning the entire spectrum from clinical and health informatics to public health informatics as applied in the healthc...