Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Ruxolitinib for the Treatment of Patients with Steroid-refractory GVHD
Abstract: For patients with hematologic malignancies and disorders, allogeneic hematopoietic stem cell transplantation offers a potentially curative treatment option. Many patients develop graft-versus-host disease (GVHD), a serious complication and leading cause of nonrelapse mortality. Corticosteroids are the standard first-line treatment for GVHD; however, patients often become steroid-refractory or remain corticosteroid-dependent. New second-line treatment options are needed to improve patient outcomes. Here we review the role of JAK1 and JAK2 in acute and chronic GVHD. We also describe the study designs of the Phase II REACH1 (NCT02953678) and the Phase III REACH2 (NCT02913261) and REACH3 (NCT03112603) clinical trials that are currently recruiting patients to evaluate the JAK1/JAK2 inhibitor ruxolitinib in patients with corticosteroid-refractory acute or chronic GVHD
Paper Talks Magazine
None
Patricia
Patricia by Patricia Revere [--------------------------------------------]
Laugh with Patricia
This book is a collection of experiences that draws on her childhood, presenting anecdotes, dilemmas, and conflicts that youth face.
"Saint Patricia."
None
Secret Lands
Illustrated by Aileen Johnston For many years the foremost name in Irish writing for children, Patricia Lynch is known for her charming classics set in an Ireland now vanished but still familiar to many whose children are now re-reading this wonderful writer. This great collection is the ideal book, gathering together all aspects of this writer's extraordinarily wide writing career.
Glow of Candlelight
None
Patricia Hayes
None
