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Realm of Tolerance
Any professional concerned with immunology will be interested in this book dedicated to the memory of Milan Hasek, former director of the Prague Institute of Experimental Biology and Genetics. Prof. Hasek was a congenial scientist and most amiable person - a personal friend of almost all leading immunologists around the world. He was displaced from his post of director in 1970, yet had a lasting impact upon his students and the group known as the Prague School of Immunogenetics. The topics covered in the contributions range from tolerance, immune network, and immunogenetics to the immunology of bacterial and viral infections. They are written by 27 of Prof. Hasek's former co-workers who emigrated to western countries around or after 1968 and became well-known and distinguished scientists in the field. The papers include their personal reflections of the Prague Institute, their impressions upon arriving abroad and their interesting experimental work since then. The book also provides a complete bibliography of their publications after leaving Czechoslovakia.
MHC + X
After the discovery of the function of MHC molecules, namely to provide the context for T cell recognition of foreign antigens, in 1974 Zinkernagel and Doherty made the first drawing of MHC+X (Fig. 1 from Zinkernagel and Doherty, Nature, 251: 547, 1974). Over the next 18 years a very large number of similar drawings ensued, some of real artistic beauty. One side of the problem, the nature of the T cell receptor, was unraveled; however, we still do not know exactly what kind of a structure the T cell receptor recognizes, al though in 1987 we learned so much about the structure of MHC molecules and antigen presentation. In schematic presentations no one is now placing the foreign antigen besid...
Origins of Inbred Mice
Origins of Inbred Mice documents the proceedings of a symposium on the state of knowledge on inbred mice held in Bethesda, Maryland, in 1978. The book is organized into seven parts. Part I provides introductory remarks on the history of the development of inbred mice. Part II contains papers that examine mutations of inbred strains of mice. Part III contains studies dealing with viruses that affect inbred mice, including those that cause leukemia and mammary tumors. Part IV examines histocompatibility genes and their antigens; cell surface antigens of mouse leukemia; the characteristics of genes of the Tla region of the mouse; and the use of recombinant inbred strains in gene mapping. Part V presents studies on differences among sublines of inbred mouse strains. The papers in Part VI focus on wild mice, covering their classification and biochemical polymorphisms. Finally, Part VIII discusses the viruses, T locus, and histocompatibility antigens of wild mice.
Leukocyte Membrane Determinants Regulating Immune Reactivity
Leukocyte Membrane Determinants Regulating Immune Reactivity is a result of the Leukocyte Culture Conference meeting held at Amsterdam in 1975. Abstracts presented in the meeting are compiled in this book. The topics of these abstracts are all under leukocyte biology and include not just lymphocytes but also monocytes, macrophages, and granulocytes. The text is composed of six major sections. The first section features abstracts that deal with ligand binding and subsequent changes in membrane. Section II focuses on the receptors on lymphocytes in the context of various subpopulations. Immune reactivity, specifically its augmentation or suppression, is the main topic of Section III. Gene products are emphasized in Section IV, while effector functions of membrane determinants are tackled in Section V. Finally, Section VI features leukocyte membrane determinants in differentiation and maturation. The book presents much detailed information that will be of great help to students or professionals in the study of biology, specifically leukocyte biology.
A New Guide to the Collections in the Library of the American Philosophical Society
Rev. ed. of: Guide to the archives and manuscript collections of the American Philosophical Society. 1966.
The Stem Cell Epistles
Human embryos, it has been said, "have no muscles, nerves, digestive system, feet, hands, face, or brain; they have nothing to distinguish them as a human being, and if one of them died, no one would mourn as they would for one of us." Consequently, early human embryos are being dismembered in laboratories around the world to produce embryonic stem cells, which, we are told, are the tools that will lead to the next quantum leap in medicine. Should Christians support such small sacrifices for something that might potentially relieve the suffering of millions, or should we vigorously oppose it? Developmental biologist and professor of biochemistry Michael Buratovich was asked such a question (...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
