Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Oxidative Metabolism in Inflammation
Mitochondrial activity is involved in different functions such as cell proliferation, metabolism, Adenosine triphosphate (ATP) generation, and cell death. Particularly, mitochondria play a major role in inflammatory signaling. They regulate the activation, differentiation, and survival of macrophages, while changes in oxidative metabolism alter polarization. Mitochondria are the main source of free radicals, and macrophages increase their oxidative stress levels when they are active. The enhancement of free radicals generation in the mitochondria can damage healthy cells, leading to inflammation. Thus, several diseases associated with an increase in mitochondrial oxidative stress can be asso...
Pedro Menendez: The Adelantado of Florida
Pedro Menendez sailed to Florida on his flagship, the San Pelayo, named after a knight who had successfully defeated the Spanish Moors 850 years earlier. There were twenty cabin boys on board the San Pelayo.Ship boys or cabin boys were from ages eleven to thirteen. Many boys were from poor families who could neither clothe nor feed them. They were servants to the officers and worked long hours, often doing the necessary dirty work onboard the ships.This courageous story is told through the eyes of one such fictitious cabin boy named Rocco that would witness the first Thanksgiving on September 8, 1565. This historic event would take place 42 years before Jamestown was settled and 55 years bef...
Novel Targets for Chronic Inflammatory Diseases: Focus On Therapeutic Drugs and Natural Compounds, volume II
This Research Topic is part of a series with: Novel Targets for Chronic Inflammatory Diseases: Focus On Therapeutic Drugs and Natural Compounds Chronic inflammation is a component of many disease conditions that affect a large group of individuals worldwide, which is characterized by persistent, low-grade inflammation and is increased in the aging population. It occurs when an initiating stimulus is not removed or if the resolution process is disrupted, resulting in a state of low-grade inflammation. It is acknowledged that chronic inflammatory diseases are involved in cardiovascular diseases, endocrine disease, neurodegenerative disease, hepatic disease, pulmonary disease, gastrointestinal ...
The Magic of Melatonin
Everything you need to know about the sleep-regulating hormone melatonin! We've always been told maintaining a healthy sleep cycle is of utmost importance to your day-to-day health. But have we ever been told why? Anyone familiar with chronobiology (the science of natural physiological rhythms) knows that the hormone melatonin is the foundation hormone for the circadian rhythm research. In fact, melatonin and sleep research is one of the most fundamental and best-known rhythms in the human body. Disturbance of the melatonin cycle due to any reason interferes with the sleep/wake cycle, which ultimately leads to a number of other neurobehavioral and psychological problems. Due to the widesprea...
Practical Medicinal Chemistry with Macrocycles
Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations
A History of Medieval Spain
Medieval Spain is brilliantly recreated, in all its variety and richness, in this comprehensive survey. Likely to become the standard work in English, the book treats the entire Iberian Peninsula and all the people who inhabited it, from the coming of the Visigoths in the fifth century to the reign of Ferdinand and Isabella. Integrating a wealth of information about the diverse peoples, institutions, religions, and customs that flourished in the states that are now Spain and Portugal, Joseph F. O'Callaghan focuses on the continuing attempts to impose political unity on the peninsula.O'Callaghan divides his story into five compact historical periods and discusses political, social, economic, ...
The Spanish Inquisition
In this completely updated edition of Henry Kamen’s classic survey of the Spanish Inquisition, the author incorporates the latest research in multiple languages to offer a new—and thought-provoking—view of this fascinating period. Kamen sets the notorious Christian tribunal into the broader context of Islamic and Jewish culture in the Mediterranean, reassesses its consequences for Jewish culture, measures its impact on Spain’s intellectual life, and firmly rebuts a variety of myths and exaggerations that have distorted understandings of the Inquisition. He concludes with disturbing reflections on the impact of state security organizations in our own time.
