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Histopathology of Preclinical Toxicity Studies
Histopathological assessment of tissue sections is an important componant of many preclinical studies which are conducted to support the safety and clinical development of novel therapeutic agents for use in the treatment of human diseases. The drug discovery process, aided by modern biotechnology, is now capable of generating highly potent, pharmacologically active agents which can give rise to quite unusual constellations of tissue pathology. The complexity and the number of histopathological findings in individual studies indicate the need for lucididy in descriptions and conclusions. In the light of these and other difficulties, this text is aimed towards bringing together into one volume a description of histopathological changes which relate to toxicity testing of therapeutic agents in the usual test species: rat, mouse, dog and non-human primate. This book is an excellent starting point for the analysis of drug-induced findings in toxicity studies.
The Seventh Gate
The autobiography of Peter Greave, born in Calcutta in the time of the Raj. He relates the tragic-comic collapse of his family's fortunes, the sufferings endured of his youth, and then heads towards the ultimate degradation as he contracts leprosy. He enters the ranks of the most outcaste of all and by the time of independence has almost entirely lost his eyesight as well as his reason to live.
Brain, Mind and the Signifying Body
This cutting-edge study of linguistic theory by one of the world's leading authors in the field of semiotics will be of interest to academics and postgraduates researching applied linguistics and advanced semiotics. In his foreword M. A. K. Halliday explains the importance of Paul J. Thibault's work to linguistics. Book jacket.
American Hereford Record and Hereford Herd Book
Brief history of Hereford cattle: v. 1, p. 359-375.
The Sand House
A revised edition of an important record of one of Doncaster's best kept secrets.
Greavsie
The autobiography of football icon Jimmy Greaves James Peter 'Jimmy' Greaves was one of the greatest footballers to have graced the English game, a goalscorer of legendary prowess. His gripping and characteristically humorous autobiography journeys from Jimmy's childhood in the East End, via his early career at Chelsea and his short and troubled stay at A.C. Milan, to his emergence as one of the great stars of sixties football while at Spurs and an outstanding England forward. Jimmy's record as a striker is extraordinary - he was the leading goalscorer in the First Division (now Premier League) for six seasons and during his playing career was never out of the top five. There are darker aspects too: the bitter disappointment of failing to make the World Cup-winning team of 1966, and the battle against the alcoholism that followed his retirement from the game. This book is both Jimmy's story and the story of football in the golden era of the fifties and sixties before money changed the game. It is populated by the great players whom Jimmy played with and against and animated by wonderful anecdotes about the game. It is an account of how football was then and how it has changed.
The Republic of Letters And the Levant
This collection of articles analyses the interests and experiences in the Levant of a number of leading western scholars of the seventeenth and eighteenth centuries, with an emphasis on the networks of learned friends throughout Europe with whom they corresponded.
