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This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike.
The book illustrates the role of quorum sensing in the food industry, agriculture, veterinary sciences, and medicine. It highlights the importance of quorum sensing in regulating diverse cellular functions in microbes, including virulence, pathogenesis, controlled-gene expression systems, and antibiotic resistance. This book also describes the role of quorum sensing in survival behavior and antibiotic resistance in bacteria. Further, it reviews the major role played by quorum sensing in food spoilage, biofilm formation, and food-related pathogenesis. It also explores the methods for the detection and quantification of quorum sensing signals. It also presents antimicrobial and anti-quorum sensing activities of medicinal plants. Finally, the book elucidates a comprehensive yet representative description of basic and applied aspects of quorum sensing inhibitors. This book serves an ideal guide for researchers to understand the implications of quorum sensing in the food industry, medicine, and agriculture.
The six volumes of A History of the Crusades will stand as the definitive history of the Crusades, spanning five centuries, encompassing Jewish, Moslem, and Christian perspectives, and containing a wealth of information and analysis of the history, politics, economics, and culture of the medieval world.
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Heresy and inquisition in France, 1200-1300 is an invaluable collection of primary sources in translation, aimed at students and academics alike. It provides a wide array of materials on both heresy (Cathars and Waldensians) and the persecution of heresy in medieval France. The book is divided into eight sections, each devoted to a different genre of source material. It contains substantial material pertaining to the setting up and practice of inquisitions into heretical wickedness, and a large number of translations from the registers of inquisition trials. Each source is introduced fully and is accompanied by references to useful modern commentaries. The study of heresy and inquisition has always aroused considerable scholarly debate; with this book, students and scholars can form their own interpretations of the key issues, from the texts written in the period itself.
This book is a volume in the Penn Press Anniversary Collection. To mark its 125th anniversary in 2015, the University of Pennsylvania Press rereleased more than 1,100 titles from Penn Press's distinguished backlist from 1899-1999 that had fallen out of print. Spanning an entire century, the Anniversary Collection offers peer-reviewed scholarship in a wide range of subject areas.