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Drug Discovery and Development
  • Language: en
  • Pages: 522

Drug Discovery and Development

This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.

Drug Repurposing
  • Language: en
  • Pages: 352

Drug Repurposing

Drug repurposing, or drug repositioning, or reprofiling, has emerged as a valid approach in modern drug discovery. The book describes tools and techniques for identifying new therapeutic potentials for existing drugs and covers the repurposing of drugs from synthetic and natural origin. It compares the costs of drug repurposing with traditional drug discovery and discusses challenges and future perspectives of drug repurposing.

Drug Discovery and Development
  • Language: en

Drug Discovery and Development

  • Type: Book
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  • Published: 2021
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  • Publisher: Unknown

This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.

Computational Drug Discovery
  • Language: en
  • Pages: 543

Computational Drug Discovery

Computational methods and understanding computational models are important in modern drug discovery. The book focuses on computational approaches that can improve the development of in silico methodologies. It includes lead hit methods, docking algorithms, computational chiral compounds, structure-based drug design, GROMACS and NAMD, structural genomics, toxicity prediction, enzyme inhibitors and peptidomimetic therapeutics

Education Skills for 21st Century Teachers
  • Language: en
  • Pages: 123

Education Skills for 21st Century Teachers

  • Type: Book
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  • Published: 2015-12-11
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  • Publisher: Springer

This monograph presents the current views, challenges and future needs of educators from a global online exchange where educators and researchers discuss the 21st century skills needed by students and teachers. The three editors, who participated in the global online research discussion group, also assumed the role of authors to summarise, analyse and celebrate the myriad of ideas generated in a topic thread that had well over a thousand responses from 26 countries. Through Comparative Analysis they then compared the posters’ ideas to some current big thinkers in education. This text promotes teachers’ voices from diverse disciplines and sectors who are united in their desire for purposeful and radical change in how teaching is carried out and what is taught. The text advocates shifting power away from government control and standardisation towards empowering teachers to guide and further develop the unique talents of diverse individuals.

Targeted Drug Delivery : Concepts and Design
  • Language: en
  • Pages: 788

Targeted Drug Delivery : Concepts and Design

  • Type: Book
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  • Published: 2014-12-08
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  • Publisher: Springer

This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

Canadian Journal of Physiology and Pharmacology
  • Language: en
  • Pages: 708

Canadian Journal of Physiology and Pharmacology

  • Type: Book
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  • Published: 2007-07
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  • Publisher: Unknown

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Pharmacology
  • Language: en
  • Pages: 472

Pharmacology

  • Type: Book
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  • Published: 1989-07
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  • Publisher: Unknown

None

Lipids in the Pathogenesis of Benign Prostatic Hyperplasia: Emerging Connections
  • Language: en

Lipids in the Pathogenesis of Benign Prostatic Hyperplasia: Emerging Connections

  • Type: Book
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  • Published: 2012
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  • Publisher: Unknown

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