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I Think I'm Outta Here
A memoir in which actor Carroll O'Connor recalls his life, discussing his service in the merchant marine during World War II, his education and early career in Dublin, and his years on "All in the Family"; and sharing the painful story of his son's cocaine addiction and suicide.
Muscle Homeostasis and Regeneration
The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases.
Clinical Trials in Older Adults
Clinical Trials in Older Adults is the first book to consider the methodological issues underlying the evaluation of new treatments in older people. Provides information on the methodology, monitoring and regulations for those planning to conduct a clinical trials involving older adults Contains examples of ongoing trials involving older adults, and presents the main characteristics of many recently published Depicts how the issues regarding older adults in clinical trials could be properly addressed with the appropriate study design and conduct Identifies key issues in performing clinical trials in older patients with common geriatric conditions, i.e. Alzheimer’s dementia, depression, low muscle mass, cancer
OECD Health Policy Studies A Good Life in Old Age? Monitoring and Improving Quality in Long-term Care
This book offers evidence and examples of useful experiences to help policy makers, providers and experts measure and improve the quality of long-term care services.
COVID-19 in the Geriatric Patient, An Issue of Clinics in Geriatric Medicine, E-Book
In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
Assessment and Treatment of Sarcopenia and Frailty in the Setting of Personalized Internal Medicine
The recognition and implementation of personalized internal medicine is of the utmost importance for physicians, nurses, dieticians and other healthcare professionals engaged in clinics. The assessment of sarcopenia and frailty, in middle-aged patients, as an embodiment of treatment personalization, is essential in settings of acute and chronic disease, both in the hospital and in ambulatory settings. This book describes various practical tools for the assessment of sarcopenia and frailty, reviews relevant findings from the current professional literature, and suggests treatment modifications for frail patients.
Dementia, Frailty and Aging
The number of older subjects is rapidly increasingly worldwide. As a consequence, the nature of clinical conditions is also changing. Traditional medicine and models of care have been based on the evaluation and treatment of single and usually acute conditions occurring in relatively young individuals. Today, the usual clinical manifestation of diseases is characterized by multiple and often chronic conditions affecting older people. In this scenario, frailty and dementia have been triggering special interest both in research and clinical settings due to their high prevalence, impact on the individual’s quality of life, and consequences for public health worldwide. These conditions aptly r...
Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy: A Translational Approach
Loss of muscle mass and increased fibrosis characterize both sarcopenia of aging and muscular dystrophy. Research is increasingly showing that these two conditions also share several pathophysiological mechanisms, including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and abnormal regulation of signaling and stress response pathways. This Research Topic will cover several mechanisms involved in aging and dystrophic sarcopenia and explore the therapeutic potential of various strategies for intervention.
Medicare Matters
Savvy, comprehensive, and authoritative, this book, written by a physician with more than thirty years experience caring for elderly patients, assesses the current state and the future prospects of Medicare, perhaps the most influential health-insurance program of our time. Christine K. Cassel draws upon the latest developments in science and medicine in a sweeping analysis of Medicare s social, demographic, institutional, political, and policy contexts. Writing in accessible language, using case studies to illustrate how policies translate to everyday lives, and applying lessons from the practice of geriatric medicine, Cassel makes a powerful argument for reforming and modernizing Medicare....
