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This report of the proceedings of the Colloquium on Occipital Seizures and Epilepsies in Children held in Milan in March 1992 covers topics such as: ontogenesis, structures and function of the occipital lobe; occipital epilepsy in children; and structures and functions of the occipital lobe.
Immunopathogenesis has recently been receiving increased interest from researchers, leading to a better understanding of the mechanisms of neurological disorders and consequently to new diagnostic approaches and therapeutic perspectives. Clinical neuroimmunology in childhood is the focus of the present volume. This book is divided into three sections. The first part deals with the relationship between the immune and the nervous systems, from antigen presentation to autoimmunity and its role in neurological disease. In the second part, the nosography of immune-mediated neurological diseases in children is described, including those primarily involving the central nervous system and those secondary to systemic immunological disorders. The last part of the book is devoted to diagnostic and therapeutic criteria.
The advances of basic sciences combined with the perspectives of developmental neurology have recently modified the traditional outlook on the evolution of motor behaviour. The maturation of neuro-anatomic structures is studied nowadays as just one facet of a complex process: the various elements of innate global patterns, the acquisition of antigravitary schemes as well as manipulative and praxic skills, control of posture and gait, ocular motility and motricity, converge to create the present picture of a continuous adaptive interaction between the child's genotype and its environment. This book stimulates the debate and the exchange of concepts between researchers and clinical specialists.
This volume provides updated information on epilepsy genes, on the clinical picture of genetic epilepsies discovered so far, and on conceptual advances in the complicated area of genotype-phenotype correlations. Recent studies on monogenic epilepsies present new insights into mechanisms whereby a mutation of a single gene, coding for an ion channel, can result in a complex epileptic phenotype. The analysis of genetically-determined epileptogenic dysplasia is advancing our understanding of the role of genes in controlling normal and pathological brain development. The pathogenic mechanisms by which gene mutations determine progressive myoclonus epilepsies offer critical opportunities to understand the role of genetic factors in neurodegenerative phenome-na associated with an even broader range of progressive epilepsy types. The specialists who have contributed to this book are outstanding international experts in their respective fields, ensuring first and foremost that the reviews are of relevance to clinicians dealing with epilepsy in their daily practice, as well as providing the highest quality scientific information for biomedical research.
Thanks to advanced imaging techniques, it is now possible to recognise in vivo structural alterations of the cortex leading in many patients to epileptic syndromes, frequently resistant to pharmacological treatment. Areas analysed in this book are: mechanisms of cortical development; animal models of neuronal migration disorders mimicking human pathology; electroclinical, neuroradiological and neuropathological studies of the different forms of cortical dysplasia. This volume includes contributions from neurologists, epileptologists, neuropaediatricians as well as paediatricians and neuroscientists, stimulating a multidisciplinary discussion to improve diagnostic and therapeutic strategies.
Prosthodontics at a Glance is a title in the popular At A Glance series and focuses on prosthodontics from diagnostics through treatment to post-operative maintenance. It is an ideal companion for all students of dentistry, clinicians and members of the dental team with an interest in prosthodontics.
This volume is based on an advanced course on epileptogenic and excitotoxic mechanisms with emphasis on development. Information on partial and generalized epileptogenesis, derived from different experimental models, is comprehensively reviewed. Special sections are devoted to anatomical, biochemical and functional aspects of the maturing brain and to their interaction with epileptogenic agents.