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A Contagious Cause
  • Language: en
  • Pages: 391

A Contagious Cause

Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer “germ,” inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. ​ A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government’s ...

Cancer on Trial
  • Language: en
  • Pages: 475

Cancer on Trial

There were no medical oncologists until a few decades ago. In the early 1960s, not only were there no such specialists, many practitioners regarded the treatment of terminally-ill cancer patients with heroic courses of chemotherapy as highly questionable. Physicians loath to assign patients randomly to competing treatments also expressed their outright opposition to the randomized clinical trials that were then relatively rare. And yet today these trials form the basis of medical oncology. How did such a spectacular change occur? How did medical oncology move from a non-entity and in some regards a reviled practice to the central position it now occupies in modern medicine?"Cancer on Trial"answers these questions by exploring how practitioners established a new style of practice, at the center of which lies the cancer clinical trial."

Between Making And Knowing: Tools In The History Of Materials Research
  • Language: en
  • Pages: 621

Between Making And Knowing: Tools In The History Of Materials Research

This book is indexed in Chemical Abstracts ServiceThis book offers a comprehensive sketch of the tools used in material research and the rich and diverse stories of how those tools came to be. We aim to give readers a sense of what tools materials researchers required in the late 20th century, and how those tools were developed and became accessible. The book is in a sense a collective biography of the components of what the philosopher of science, Ian Hacking, calls the 'instrumentarium' of materials research. Readers should gain an appreciation of the work materials researchers put into developing and using such tools, and of the tremendous variety of such tools. They should also gain some insight into the material (and hence financial) prerequisites for materials research. Materials research requires funding for the availability and maintenance of its tools; and the category of tools encompasses a broad range of substances, apparatus, institutions, and infrastructure.

The Life of a Virus
  • Language: en
  • Pages: 422

The Life of a Virus

We normally think of viruses in terms of the devastating diseases they cause, from smallpox to AIDS. But in The Life of a Virus, Angela N. H. Creager introduces us to a plant virus that has taught us much of what we know about all viruses, including the lethal ones, and that also played a crucial role in the development of molecular biology. Focusing on the tobacco mosaic virus (TMV) research conducted in Nobel laureate Wendell Stanley's lab, Creager argues that TMV served as a model system for virology and molecular biology, much as the fruit fly and laboratory mouse have for genetics and cancer research. She examines how the experimental techniques and instruments Stanley and his colleagues developed for studying TMV were generalized not just to other labs working on TMV, but also to research on other diseases such as poliomyelitis and influenza and to studies of genes and cell organelles. The great success of research on TMV also helped justify increased spending on biomedical research in the postwar years (partly through the National Foundation for Infantile Paralysis's March of Dimes)—a funding priority that has continued to this day.

Global Transformations in the Life Sciences, 1945–1980
  • Language: en
  • Pages: 292

Global Transformations in the Life Sciences, 1945–1980

The second half of the twentieth century brought extraordinary transformations in knowledge and practice of the life sciences. In an era of decolonization, mass social welfare policies, and the formation of new international institutions such as UNESCO and the WHO, monumental advances were made in both theoretical and practical applications of the life sciences, including the discovery of life’s molecular processes and substantive improvements in global public health and medicine. Combining perspectives from the history of science and world history, this volume examines the impact of major world-historical processes of the postwar period on the evolution of the life sciences. Contributors ...

Airport Urbanism
  • Language: en
  • Pages: 291

Airport Urbanism

Thirty years ago, few residents of Asian cities had ever been on a plane, much less outside their home countries. Today, flying, and flying abroad, is commonplace. How has this leap in cross-border mobility affected the design and use of such cities? And how is it accelerating broader socioeconomic and political changes in Asian societies? In Airport Urbanism, Max Hirsh undertakes an unprecedented study of airport infrastructure in five Asian cities—Bangkok, Hong Kong, Shenzhen, Kuala Lumpur, and Singapore. Through this lens he examines the exponential increase in international air traffic and its implications for the planning and design of the contemporary city. By investigating the low-c...

Atomic Adventures
  • Language: en
  • Pages: 573

Atomic Adventures

Whether you are a scientist or a poet, pro-nuclear energy or staunch opponent, conspiracy theorist or pragmatist, James Mahaffey's books have served to open up the world of nuclear science like never before. With clear explanations of some of the most complex scientific endeavors in history, Mahaffey's new book looks back at the atom's wild, secretive past and then toward its potentially bright future. Mahaffey unearths lost reactors on far flung Pacific islands and trees that were exposed to active fission that changed gender or bloomed in the dead of winter. He explains why we have nuclear submarines but not nuclear aircraft and why cold fusion doesn't exist. And who knew that radiation counting was once a fashionable trend? Though parts of the nuclear history might seem like a fiction mash-up, where cowboys somehow got a hold of a reactor, Mahaffey's vivid prose holds the reader in thrall of the infections energy of scientific curiosity and ingenuity that may one day hold the key to solving our energy crisis or sending us to Mars.

Volcanoes
  • Language: en
  • Pages: 677

Volcanoes

Volcanoes are essential elements in the delicate global balance of elemental forces that govern both the dynamic evolution of the Earth and the nature of Life itself. Without volcanic activity, life as we know it would not exist on our planet. Although beautiful to behold, volcanoes are also potentially destructive, and understanding their nature is critical to prevent major loss of life in the future. Richly illustrated with over 300 original color photographs and diagrams the book is written in an informal manner, with minimum use of jargon, and relies heavily on first-person, eye-witness accounts of eruptive activity at both "red" (effusive) and "grey" (explosive) volcanoes to illustrate ...

Reordering Life
  • Language: en
  • Pages: 363

Reordering Life

  • Type: Book
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  • Published: 2017-05-19
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  • Publisher: MIT Press

How the regimes governing biological research changed during the genomics revolution, focusing on the Human Genome Project. The rise of genomics engendered intense struggle over the control of knowledge. In Reordering Life, Stephen Hilgartner examines the “genomics revolution” and develops a novel approach to studying the dynamics of change in knowledge and control. Hilgartner focuses on the Human Genome Project (HGP)—the symbolic and scientific centerpiece of the emerging field—showing how problems of governance arose in concert with new knowledge and technology. Using a theoretical framework that analyzes “knowledge control regimes,” Hilgartner investigates change in how contro...

Postgenomics
  • Language: en
  • Pages: 286

Postgenomics

Ten years after the Human Genome Project’s completion the life sciences stand in a moment of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in research methodology, funding, scientific labor, and disciplinary structures. Postgenomics is transforming our understanding of disease and health, our environment, and the categories of race, class, and gender. At the same time, the gene retains its centrality and power in biological and popular discourse. The contributors to Postgenomics analyze these ruptures and continuities and place them in historical, social, and political context. Postgenomics, they argue, forces a rethinking of the genome itself, and opens new territory for conversations between the social sciences, humanities, and life sciences. Contributors. Russ Altman, Rachel A. Ankeny, Catherine Bliss, John Dupré, Michael Fortun, Evelyn Fox Keller, Sabina Leonelli, Adrian Mackenzie, Margot Moinester, Aaron Panofsky, Sarah S. Richardson, Sara Shostak, Hallam Stevens