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A Contagious Cause
Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer “germ,” inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government’s ...
Selling Science
Today, when many parents seem reluctant to have their children vaccinated, even with long proven medications, the Salk vaccine trial, which enrolled millions of healthy children to test an unproven medical intervention, seems nothing short of astonishing. In Selling Science, medical historian Stephen E. Mawdsley recounts the untold story of the first large clinical trial to control polio using healthy children—55,000 healthy children—revealing how this long-forgotten incident cleared the path for Salk’s later trial. Mawdsley describes how, in the early 1950s, Dr. William Hammon and the National Foundation for Infantile Paralysis launched a pioneering medical experiment on a previously ...
Rabbits with Horns and Other Astounding Viruses
Viruses are the smallest living things known to science, yet they hold the entire planet in their sway. Rabbits with Horns and Other Astounding Viruses explores the bizarre places viruses dwell, and considers the often unexpected ways they influence our world. From agricultural production and crystal caves to rabbits with horns and cervical cancer, viruses are behind many of the wonders—some fascinating, some frightening—of the natural world, as well as some of our greatest medical challenges. Through his engaging considerations of the tobacco mosaic virus, viruses in ocean algae, and the human papillomavirus, award-winning science writer Carl Zimmer brings us up to speed on the nuances and depth of today's cutting-edge scientific research on virology.
The Life of a Virus
We normally think of viruses in terms of the devastating diseases they cause, from smallpox to AIDS. But in The Life of a Virus, Angela N. H. Creager introduces us to a plant virus that has taught us much of what we know about all viruses, including the lethal ones, and that also played a crucial role in the development of molecular biology. Focusing on the tobacco mosaic virus (TMV) research conducted in Nobel laureate Wendell Stanley's lab, Creager argues that TMV served as a model system for virology and molecular biology, much as the fruit fly and laboratory mouse have for genetics and cancer research. She examines how the experimental techniques and instruments Stanley and his colleagues developed for studying TMV were generalized not just to other labs working on TMV, but also to research on other diseases such as poliomyelitis and influenza and to studies of genes and cell organelles. The great success of research on TMV also helped justify increased spending on biomedical research in the postwar years (partly through the National Foundation for Infantile Paralysis's March of Dimes)—a funding priority that has continued to this day.
The Arts of the Microbial World
"The Arts of the Microbial World explores how Japanese scientists and skilled workers sought to use the microbe's natural processes to create new products, from soy-sauce mold starters to MSG and from vitamins to statins. In traditional brewing houses as well as in the food, fine chemical, and pharmaceutical industries across Japan, they showcased their ability to deal with the enormous sensitivity and variety of the microbial world. Victoria Lee's careful study offers a lush historical example of a society where scientists asked microbes for what they termed "gifts." Lee's story ranges from the microbe's integration into Japan as an imported concept to its precise application in recombinant...
A Planet of Viruses
The past year has been one of viral panic--panic about viruses, that is. Through headlines, public health warnings, and at least one homemade hazmat suit, we were reminded of the powerful force of viruses. They are the smallest living things known to science, yet they can hold the entire planet in their sway. A Planet of Viruses is Carl Zimmer's eye-opening look at the hidden world of viruses. Zimmer, the popular science writer and author of National Geographic's award-winning blog The Loom, has updated this edition to include the stories of new outbreaks, such as Ebola, MERS, and chikungunya virus; new scientific discoveries, such as a hundred-million-year-old virus that infected the common...
Between Making And Knowing: Tools In The History Of Materials Research
This book is indexed in Chemical Abstracts ServiceThis book offers a comprehensive sketch of the tools used in material research and the rich and diverse stories of how those tools came to be. We aim to give readers a sense of what tools materials researchers required in the late 20th century, and how those tools were developed and became accessible. The book is in a sense a collective biography of the components of what the philosopher of science, Ian Hacking, calls the 'instrumentarium' of materials research. Readers should gain an appreciation of the work materials researchers put into developing and using such tools, and of the tremendous variety of such tools. They should also gain some insight into the material (and hence financial) prerequisites for materials research. Materials research requires funding for the availability and maintenance of its tools; and the category of tools encompasses a broad range of substances, apparatus, institutions, and infrastructure.Between Nature and Society: Biographies of Materials (Part of A World Scientific Encyclopedia of the Development and History of Materials Science)
A Tale of Two Viruses
In 1965, French microbiologist André Lwoff was awarded the Nobel Prize in Physiology or Medicine for his work on lysogeny—one of the two types of viral life cycles—which resolved a contentious debate among scientists about the nature of viruses. A Tale of Two Viruses is the first study of medical virology to compare the history of two groups of medically important viruses—bacteriophages, which infect bacteria, and sarcoma agents, which cause cancer—and the importance of Lwoff’s discovery to our modern understanding of what a virus is. Although these two groups of viruses may at first glance appear to have little in common, they share uniquely parallel histories. The lysogenic cycl...
Planet of Microbes
This book takes readers into the latest discoveries about early microbial life, where findings from the earth's furthest extremes are seeking to reshape the future of our planet and ourselves. As scientists take the next step in applying the lessons of popular and controversial research, the world's tiniest, and sometimes most dangerous, microorganisms are being tapped as allies in achieving better health and sustainable energy, while revealing fundamental clues to the mystery of where we came from.--Provided by publisher.
Postgenomics
Ten years after the Human Genome Project’s completion the life sciences stand in a moment of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in research methodology, funding, scientific labor, and disciplinary structures. Postgenomics is transforming our understanding of disease and health, our environment, and the categories of race, class, and gender. At the same time, the gene retains its centrality and power in biological and popular discourse. The contributors to Postgenomics analyze these ruptures and continuities and place them in historical, social, and political context. Postgenomics, they argue, forces a rethinking of the genome itself, and opens new territory for conversations between the social sciences, humanities, and life sciences. Contributors. Russ Altman, Rachel A. Ankeny, Catherine Bliss, John Dupré, Michael Fortun, Evelyn Fox Keller, Sabina Leonelli, Adrian Mackenzie, Margot Moinester, Aaron Panofsky, Sarah S. Richardson, Sara Shostak, Hallam Stevens
