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Coenzyme Q10: Uses, Health Effects and Role in Disease reviews the current knowledge and evidence of the potential clinical applications of Coenzyme Q10 (CoQ10). CoQ10 is a lipophilic molecule composed by a bezonquinone ring conjugated to a ten-carbon isoprenoid side chain. It exists in two molecular forms, ubiquinone and ubiquinol, which are the basis for its antioxidant properties. CoQ10 also plays an essential role in cellular metabolism to produce ATP, which provides energy for muscle contraction and other vital cellular functions. Most of the ATP production occurs in the inner mitochondrial membrane, where coenzyme Q is found. The authors review the protective effects of CoQ10 on intense physical exercise, reducing muscle damage and improving physical performance. Evidence of secondary CoQ10 deficiency in disease and in pharmacotherapy is discussed, highlighting putative mechanisms to account for this deficit together with examples of therapeutic intervention. Secondary CoQ10 deficiencies are important to identify as clinical benefit can be elicited following treatment with CoQ10 or its associated analogues.
After a long period of neglect, emotions have become an important topic within literary studies. This collection of essays stresses the complex link between aesthetic and non-aesthetic emotional components and discusses emotional patterns by focusing on the practice of writing as well as on the impact of such patterns on receptive processes. Readers interested in the topic will be presented with a concept of aesthetic emotions as formative both within the writing and the reading process. Essays, ranging in focus from the beginning of modern drama to digital formats and theoretical questions, examine examples from English, German, French, Russian and American literature. Contributors include Angela Locatelli, Vera Nünning, and Gesine Lenore Schiewer.
The Three Apostles of Russian Music looks at three figures in the Soviet avant-garde who led modernist music in the 1920s. Mosolov, Popov, and Roslavets were popular composers who are now unfortunately forgotten. These remarkable musicians produced compositions like the sensational machine music Foundry by Mosolov. The first symphony by Popov attracted musicians in Europe and America but was banned after the premiere, while Roslavets discovered serialism before Schoenberg, opening up a new trend in modernism. This book is the first study in English of the work, lives, and legacies of these “apostles” of the Russian avant-garde.
Vladimir Sorokin is the most prominent and the most controversial contemporary Russian writer. Having emerged as a prose writer in Moscow’s artistic underground in the late 1970s and early 80s, he became visible to a broader Russian audience only in the mid-1990s, with texts shocking the moralistic expectations of traditionally minded readers by violating not only Soviet ideological taboos, but also injecting vulgar language, sex, and violence into plots that the postmodernist Sorokin borrowed from nineteenth-century literature and Socialist Realism. Sorokin became famous when the Putin youth organization burned his books in 2002 and he picked up neo-nationalist and neo-imperialist discourses in his dystopian novels of the 2000s and 2010s, making him one of the fiercest critics of Russia’s “new middle ages,” while remaining steadfast in his dismantling of foreign discourses.
The author of this book made his debut as an athleticshistorian in 1948 aged 26. When in close co-operationwith his friend Donald H. Potts he edited A Handbook onOlympic Games Track and Field Athletics', a statisticalwork which among other things offered the first-everWorld List of the 100 best track and field performancesof all time ......
Awe-inspiring classical ruins, dramatic volcanic landscapes, stunning coastline and towns which bear witness to the island's fascinating yet turbulent history - welcome to Sicily. Your DK Eyewitness Top 10 travel guide ensures you'll find your way around Sicily with absolute ease. Our newly updated Top 10 travel guide breaks down the best of Sicily into helpful lists of ten - from our own selected highlights to the best museums, places to eat, shops and Sicilian feasts and processions. You'll discover: -Seven easy-to-follow itineraries, perfect for a day-trip, a weekend, or a week -Detailed Top 10 lists of Sicily's must-sees, including detailed descriptions of Palermo, Monreale, the Aeolian ...
The essential dining companion for your French vacation rental (and back home) A trip to the grocery store while vacationing in a foreign country can be a frustrating ordeal. How to choose the best seafood (what is the deal with the tiny packages of fish?), proper farmers’ market etiquette (is it okay to touch the veggies?), and choosing the right checkout line (there are different kinds?) can all lead to moments of confusion, and asking for help is not so easy with a language barrier. When author Lynne Martin tried living as locals do in France, she found making her own meals nearly impossible. Unfamiliar with cuts of meat and unable to decipher labels or cooking instructions, she was surrounded by delicious produce but lost when it came to utilizing it in French cooking. Chef Deborah Scarborough came to her rescue, and now, in Eat Like a Local in France, both share their tips for other travelers looking to rock their vacation cooking or explore French cuisine at home. In addition to 50 recipes, there are guides to wine and cheese, tips for stocking a rental home, and information about French kitchen basics.