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Unmasking metabolic dependencies for anti-cancer treatment in cancer
  • Language: en
  • Pages: 157

Unmasking metabolic dependencies for anti-cancer treatment in cancer

Over the last decade, our understanding of metabolism in the context of cancer has evolved greatly. It is now evident that altered cellular metabolism is an integral effector of tumorigenesis that is intricately intertwined with cell signaling as well as genetic and epigenetic regulation of diverse tumor programs. Recognizing the dysregulation of cellular metabolism as an important aspect of tumor function has offered new potential direction to seek clinical benefit by providing targets for the development of novel therapeutics. To-date, several small molecule inhibitors that target tumor or immune cell metabolism are being explored in active clinical trials as either preventive, stand-alone, or adjuvant therapies for various malignancies. Thus, identifying critical metabolic vulnerabilities in pre-neoplastic cells, cancer cells, and immune cells has direct and timely relevance for developing additional treatment and preventative strategies against cancer.

Characterizing the Multi-faceted Dynamics of Tumor Cell Plasticity
  • Language: en
  • Pages: 336
Bioinformatics and Biomedical Engineering
  • Language: en
  • Pages: 485

Bioinformatics and Biomedical Engineering

This volume constitutes the proceedings of the 9th International Work-Conference on IWBBIO 2020, held in Maspalomas, Gran Canaria, Spain, in June 2022. The total of 75 papers presented in the proceedings, was carefully reviewed and selected from 212 submissions. The papers cover the latest ideas and realizations in the foundations, theory, models, and applications for interdisciplinary and multidisciplinary research encompassing disciplines of computer science, mathematics, statistics, biology, bioinformatics, and biomedicine.

Interventional Therapy of Hepatocellular Carcinoma
  • Language: en
  • Pages: 113
Insights in Molecular Diagnostics and Therapeutics: 2021
  • Language: en
  • Pages: 196

Insights in Molecular Diagnostics and Therapeutics: 2021

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

AACR 2017 Proceedings: Abstracts 1-3062
  • Language: en
  • Pages: 3186

AACR 2017 Proceedings: Abstracts 1-3062

The AACR Annual Meeting highlights the best cancer science and medicine from institutions all over the world. Attendees are invited to stretch their boundaries, form collaborations, attend sessions outside their own areas of expertise, and learn how to apply exciting new concepts, tools, and techniques to their own research. Part A contains abstracts 1-3062 accepted for the 2017 meeting.

Immuno-Oncology Crosstalk and Metabolism
  • Language: en
  • Pages: 223

Immuno-Oncology Crosstalk and Metabolism

This book discusses the novel metabolic cross-talk between immune and tumor cells in the tumor microenvironment that promotes their growth and progression. It also describes deregulated metabolism in cancer cells that promotes suppressive and cancer cell-favourable microenvironment. Further, the book provides novel insights on the metabolic changes in immune cells that promote tumor cell growth and survival. In turn, it also reviews the involvement of immuno-onco metabolic cross-talk in the development of resistance to chemo-radiation therapy (CRT) in tumor cells. Lastly, it also explores the potential of immuno-oncology metabolism as a therapeutic approach against tumor cells.

Accessions List, South Asia
  • Language: en
  • Pages: 694

Accessions List, South Asia

  • Type: Book
  • -
  • Published: 1988
  • -
  • Publisher: Unknown

Records publications acquired from Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka, by the U.S. Library of Congress Offices in New Delhi, India, and Karachi, Pakistan.

A Bibliography of Doctoral Dissertations Accepted by Indian Universities, 1857-1970
  • Language: en
  • Pages: 428
Rajasthan Bibliographic Index in Social Science
  • Language: en
  • Pages: 438