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A Practical Guide to Scientific Writing in Chemistry
Successful completion of postgraduate studies, especially PhD, and career advancement in academia strongly depend on the ability to publish scientific papers or books and attract research grants. However, many chemical scientists find preparing scientific papers and research grant and book proposals difficult; partly because of insufficient training in writing and partly because there are few practical books to enable them to learn the art. This step-by-step practical guide is intended mainly for postgraduate students and early career researchers in chemical science and the libraries that serve them but will also be useful to other scientists. Key Features: Improves the reader’s chances of getting their manuscript published in chemistry journals. Increases the likelihood of winning research grants in chemistry. Takes a “lead by the hand” approach. Contains chapters on the preparation of graphical abstracts and research highlights. Uses sketches and other illustration styles to aid mental visualization of concepts. Contains practical examples taken from published papers and successful research grant proposals.
Determinants of synaptic information transfer: From Ca2+ binding proteins to Ca2+ signaling domains
The cytoplasmic free Ca2+ concentration ([Ca2+]i) is a key determinant of neuronal information transfer and processing. It controls a plethora of fundamental processes, including transmitter release and the induction of synaptic plasticity. This enigmatic second messenger conveys its wide variety of actions by binding to a subgroup of Ca2+ binding proteins (CaBPs) known as “Ca2+ sensors”. Well known examples of Ca2+ sensors are Troponin-C in skeletal muscle, Synaptotagmin in presynaptic terminals, and Calmodulin (CaM) in all eukaryotic cells. Since the levels of [Ca2+]i directly influence the potency of Ca2+ sensors, the Ca2+ concentration is tightly controlled by several mechanisms incl...
The regulated secretory pathway in neuroendocrine cells
The regulated secretory pathway is a hallmark of neuroendocrine cells. This process comprises many sequential steps, which include ER-associated protein synthesis, post-translational modification of proteins in the Golgi complex, sorting and packing of secretory proteins into carrier granules, cytoskeleton-based granule transport towards the plasma membrane and tethering, docking and fusion of granules with specialized releasing zones. Each stage is subjected to a rigorous regulation by a plethora of factors that function in a spatially and temporarily coordinated fashion. Much effort has been devoted to characterize the precise role of the regulatory proteins participating in the different steps of this process and to identify new factors in order to obtain a unifying picture of the secretory pathway. In spite of this and given the enormous complexity of the process, certain stages are not fully understood yet and many players remain to be identified. The aim of this Research Topic is to gather review articles and original research papers on the molecular mechanisms that govern and ensure the correct release of neuropeptides.
Presynaptic Terminals
This book brings together leading international experts to discuss recent advances in functional studies on key proteins and protein complexes involved in each synaptic vesicle phase. These include proteins that control the final step of neurotransmitter release, in response to a neural signal, and the first step of vesicle endocytosis, which helps maintain stable neurotransmitter release in response to unceasing neural signals arriving at presynaptic terminals. Neural networks transmit input and output signals of action potentials using chemical synapses. The strength of the signal from one to another neuron can be tuned by the neural signal itself as it induces Ca2+ entry and by other neur...
Methods for Synaptic Interrogation
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Data Visualization Handbook
The data visualization handbook is a practical guide to creating compelling graphics to explain or explore data. It is primarily aimed for designers, journalists, researchers, analysts, and other professionals who want to learn the basics of visualization, but also includes plenty of material for people with intermediate level visualization skills.
