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Leading a Surgical Revolution
This book describes the 60-year history of the AO Foundation and its impact on the treatment of bone trauma. Originally founded by a group of Swiss surgeons, the AO has since established its osteosynthesis treatment approach to trauma, using surgery and implants, as the global standard. The AO successfully convinced the medical community that surgery of bone trauma was superior to the standard conservative treatment using plaster casts. This new technique meant that patients no longer had to spend long weeks at the hospital in traction, and prevented many disabilities. This book describes the struggle with the medical community, explains how the AO surgeons enlisted the support of an entire ...
Refinements to Animal Models for Biomedical Research
There is some talk about an antibiotic Armageddon, wherein untreatable post-operative infections and similarly untreatable complications after chemotherapy will occur. The now famous “O’Neill Report” suggests that, by 2050, more people could die from resistant bacterial infections than from cancer. We are still learning about all the subtle drivers of antibiotic resistance, realizing that we need a single “whole health” coordinated policy. We ingest what we sometimes feed to animals, yet there does not seem to be any new classes of antibiotics on the horizon. Maybe there is something that has been around forever that could could to our rescue: bacteriophages. Nevertheless, we have ...
A Drug Holiday Reduces the Frequency and Severity of Medication-related Osteonecrosis of the Jaw in a Minipig Model
Abstract: Treatment of medication-related osteonecrosis of the jaw (MRONJ) is challenging and no clear consensus has been achieved. This study investigated preventive measures recommended for tooth extractions under antiresorptive (AR) treatment and the role of discontinuation of AR therapy to avoid the onset of MRONJ in a minipig model. Thirty-six Göttingen minipigs were divided into four groups. Group 1 (negative control): tooth extractions but no zoledronate (ZOL). Group 2 (positive control): weekly ZOL infusions for 12 weeks followed by tooth extractions without wound management followed by 8 weeks of ZOL treatment. Group 3: weekly ZOL infusions for 12 weeks followed by tooth extraction...
Anesthesia and Analgesia in Laboratory Animals
Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic and postoperative care requirements associated with experimental interventions. Fully revised and updated, this new edition provides the reader with agents, methods and techniques for anesthesia and analgesia that ensure humane, reproducible, and successful procedural outcomes. Sections cover ethical, regulatory and scientific considerations, principles of anesthesia and analgesia, anesthetic equipment and monitoring, periprocedural care, including dedicated chapters to the assessment and management of pain in laboratory species, and practical considerations by species, including relevant anatomy, phy...
Transactions of the Annual Meeting of the Orthopaedic Research Society
Consists of the transactions of the 22nd- annual meeting of the society.
Darstellung Des Fabriks- Und Gewerbswesens in Seiem Gegenwärtigen Zustande, Zeiter Theil, Erster Band
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Praxishandbuch DSGVO
Die Einhaltung der DSGVO und des BDSG stellt nach wie vor eine große Herausforderung für Unternehmen dar. Beide Regelwerke zeichnen sich einerseits durch umfassende Regelungen, andererseits durch sehr abstrakte Vorgaben aus. Die Datenschutzbehörden äußern sich nur zu einzelnen Themen und dann im Regelfall mit strengen Positionen. Es bleibt also den Unternehmen selbst überlassen, pragmatische und praxistaugliche Lösungen zu entwickeln. Vor diesem Hintergrund richtet sich das Praxishandbuch an alle Datenschutzpraktiker. Es liefert umfassende Lösungen für die Vielzahl an Fragestellungen, die sich im Unternehmen ganz praktisch bei der Einhaltung der datenschutzrechtlichen Anforderungen ...
