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Biology and Pathogenesis of Legionella
Legionella pneumophila was first isolated as the causative agent of a deadly infectious pneumonia at a convention of the American Legion forty years ago. Since then, Legionnaires’ disease continues to be a significant public health concern. Today, our understanding of the Legionella genus, comprising environmental bacteria and opportunistic human pathogens, has dramatically increased. The study of how pathogenic Legionella interact with host cells, both protozoan and mammalian, has not only taught us about host-pathogen interactions but has revealed novel and unexpected insights into human cell biology and immunology. The capacity of pathogenic Legionella to commandeer cellular processes s...
Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases
Based on a conference on Oxidative Stress and Redox Regulation, held at the Pasteur Institute, Paris, this work examines fundamental, chemical, biological and medical studies of free radicals on different targets and the consequences of their reactivity. It covers the chemistry and biochemistry of free radicals, free radicals as second messengers t
Science
None
Neuroimmune System
The book explores the intricate connections between the nervous and immune systems in the context of neurodegenerative disorders, offering a comprehensive overview of the bidirectional communication between these systems and their implications for disease progression and therapeutic interventions. The book aims to understand the recent developments in the field of neuroimmune communication. Key Features: In-depth analysis of immunological biomarkers and therapeutic targets for neurodegenerative disorders. Exploration of the role of glial cells in neuroimmune interactions and their dual nature in disease pathology. Examination of short- and long-range interactions between the central nervous ...
Priorité cerveau
Aujourd’hui, 15 millions de personnes en France souffrent d’une, voire de plusieurs maladies du cerveau : migraines, dépression, troubles du sommeil ou encore maladie d’Alzheimer ou de Parkinson, etc. Ce chiffre ne cesse de croître. La connaissance du cerveau et notre compréhension des mécanismes à l’origine de ces maladies constituent donc un enjeu collectif majeur face au vieillissement de la population. Si, au cours des dernières années, les maladies neurologiques ont bénéficié de certains progrès thérapeutiques, les traitements curatifs font encore souvent défaut et les ressources financières sont insuffisantes face aux exigences et aux nécessités de la recherche....
