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Clearance of apoptotic cells is essential for proper development, homeostasis and termination of immune responses in multicellular organisms. Thus, cellular and molecular players taking part in the sequential events of this process are of great interest. Research in the last 20 years has indicated that specific ligands and receptors take part in the attraction of immune cells toward apoptotic targets and in the interactions between apoptotic cells and professional as well as non-professional phagocytes that engulf them. Moreover, phagocytosis of apoptotic cells (efferocytosis) leads to significant phenotypic changes in the engulfing cells suggesting that it is a major fate-determining event ...
Voila! is a motivating French course taking students from beginner level through to GCSE and is aimed at a wide range of abilities. It includes the three-part lesson, assessment for learning and thinking skills.
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A lively history of French opera in its cultural and historical context by one of France's leading musicologists.
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